Eliminating health disparities is a major unmet need in our society. The concern is not only for equity and social justice. It will be impossible to fulfill our national goal to have a healthy population without addressing this need. Achieving this goal can be significantly enhanced by establishing health disparities research centers across the nation that are ready to implement an agenda of research, education, training and community outreach activities to support the goal of the NIMHD to eliminate disparities. Implementing these activities requires an effective administrative structure that provides support and facilitates the execution of successful initiatives and research plans. Based on our experience in the previous grant cycle, it would not be possible to operate the Center with all of its activities and maintain institutional support without a visible and efficient administrative core. The Administrative Core structure and function proposed in this application will be critical to achieve the major goals of our Center and the specific aims proposed by its other cores. For instance, we put significant attention into having an Administrative Core that addresses the needs of a young growing center. This plan provides adequate oversight through effective and experienced internal and external scientific leadership and avoids unnecessary bureaucracy and also fits well within the structure of the Center. The structure proposed for the Center was crafted in such a way that it addresses all LLU policies with respect to university centers, institutes and departments, and includes required oversight by LLU administration through an Internal Advisory panel. This was important to qualify for financial support in proportion to extramural funding generated similarly by other centers and departments. The External Advisory Panel includes a cadre of experienced national leaders in health disparities that advise the Center Director and leadership team.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
4P20MD006988-05
Application #
9003817
Study Section
Special Emphasis Panel (ZMD1)
Project Start
Project End
2018-01-31
Budget Start
2016-02-01
Budget End
2017-01-31
Support Year
5
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Loma Linda University
Department
Type
DUNS #
009656273
City
Loma Linda
State
CA
Country
United States
Zip Code
92350
Cajigas-Du Ross, Christina K; Martinez, Shannalee R; Woods-Burnham, Leanne et al. (2018) RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance. Oncotarget 9:30363-30384
Rowland, Leah K; Campbell, Petreena S; Mavingire, Nicole et al. (2018) Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death. J Cell Biochem :
Woods-Burnham, Leanne; Cajigas-Du Ross, Christina K; Love, Arthur et al. (2018) Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells. Sci Rep 8:15063
Woods-Burnham, Leanne; Stiel, Laura; Wilson, Colwick et al. (2018) Physician Consultations, Prostate Cancer Knowledge, and PSA Screening of African American Men in the Era of Shared Decision-Making. Am J Mens Health 12:751-759
Campbell, Petreena S; Mavingire, Nicole; Khan, Salma et al. (2018) AhR ligand aminoflavone suppresses ?6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells. J Cell Physiol 234:108-121
Cordero, Kathia; Coronel, Gemma G; Serrano-Illán, Miguel et al. (2018) Effects of Dietary Vitamin E Supplementation in Bladder Function and Spasticity during Spinal Cord Injury. Brain Sci 8:
Greer-Phillips, Suzanne E; Sukomon, Nattakan; Chua, Teck Khiang et al. (2018) THE AER2 RECEPTOR FROM VIBRIO CHOLERAE IS A DUAL PAS-HEME OXYGEN SENSOR. Mol Microbiol :
Gonda, Amber; Kabagwira, Janviere; Senthil, Girish N et al. (2018) Exosomal survivin facilitates vesicle internalization. Oncotarget 9:34919-34934
Lewis, Charlotte M; Gamboa-Maldonado, Thelma; Carlos Belliard, Juan et al. (2018) Patient and Community Health Worker Perceptions of Community Health Worker Clinical Integration. J Community Health :
Descorbeth, Magda; Figueroa, Karen; Serrano-Illán, Miguel et al. (2018) Protective effect of docosahexaenoic acid on lipotoxicity-mediated cell death in Schwann cells: Implication of PI3K/AKT and mTORC2 pathways. Brain Behav 8:e01123

Showing the most recent 10 out of 106 publications