This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.8 month studyBackground: Sexually transmitted disease (STD) rates continue to rise in this country. Herpes Simplex Virus (HSV) is one of the most common STDs with reportedly 60 million people infected in the United States and the majority are unaware they are infected. This study will determine the prevalence rate of HSV in a large Southeastern metropolitan urban primary care practice. Methods: ARM I- Participants who were sexually active in the past year and 18 years or older were tested for HSV-2 using type-specific serology. The sample included 185 participants who presented to a primary care practice, then on to the research cemter. Demographic information and a sexual history were obtained from all participants. Participants were tested for HSV-2 antibodies and a history of prior HSV infection and testing were obtained.ARM II - Participants who are expectant mothers - total recruited 161 Methodology sameArm III - Participant were non sexually active. total recruited - 46
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