Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this core is to provide project investigators with a resource for expert consultation, technical training, and state-of-the-art instrumentation to enable advancement of their research efforts through the application of DNA microarray analysis, qPCR and protein based ('proteomic') approaches. The DNA microarray analysis component permits investigators to use DNA microarray screening technology to perform comprehensive gene expression profiling through application of Affymetrix GeneChip screening and advanced computational/statistical analysis methods. The proteomics component provides investigators with technical assistance and instrumentation resources to use conventional and cutting edge protein biochemistry-based technologies including multiplex bead array and surface plasmon technology to address questions of protein function.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016434-09
Application #
7959855
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2009-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
9
Fiscal Year
2009
Total Cost
$232,238
Indirect Cost

  Institution

Name
Medical University of South Carolina
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Moreno-Rodriguez, Ricardo A; Krug, Edward L; Reyes, Leticia et al. (2017) Linear array of multi-substrate tracts for simultaneous assessment of cell adhesion, migration, and differentiation. Biotechniques 63:267-274
Soiberman, Uri; Foster, James W; Jun, Albert S et al. (2017) Pathophysiology of Keratoconus: What Do We Know Today. Open Ophthalmol J 11:252-261
Karousou, Evgenia; Misra, Suniti; Ghatak, Shibnath et al. (2017) Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer. Matrix Biol 59:3-22
Liu, Gang; Cooley, Marion A; Jarnicki, Andrew G et al. (2016) Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases. JCI Insight 1:
Menon, Vinal; Junor, Lorain; Balhaj, Marwa et al. (2016) A Novel Ex Ovo Banding Technique to Alter Intracardiac Hemodynamics in an Embryonic Chicken System. J Vis Exp :
Dupuis, Loren E; Doucette, Lorna; Rice, A Kittrell et al. (2016) Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican. Dev Dyn 245:1029-42
Olsen, T R; Mattix, B; Casco, M et al. (2015) Manipulation of cellular spheroid composition and the effects on vascular tissue fusion. Acta Biomater 13:188-98
Stevens, Shawn M; Brown, LaShardai N; Ezell, Paula C et al. (2015) The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration. J Vis Exp :
Menon, Vinal; Eberth, John F; Goodwin, Richard L et al. (2015) Altered Hemodynamics in the Embryonic Heart Affects Outflow Valve Development. J Cardiovasc Dev Dis 2:108-124
Dupuis, Loren E; Berger, Matthew G; Feldman, Samuel et al. (2015) Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly. J Mol Cell Cardiol 84:70-80

Showing the most recent 10 out of 154 publications