Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Will support a project to dissect immune regulatory mechanisms in the pathogenesis of influenza, tuberculosis, HIV and the modulation of anti-tumor responses in myeloma/renal cell carcinoma.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
3P20RR016437-09S1
Application #
7893949
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Program Officer
Gorospe, Rafael
Project Start
2009-09-17
Project End
2012-09-16
Budget Start
2009-09-17
Budget End
2012-09-16
Support Year
9
Fiscal Year
2009
Total Cost
$307,533
Indirect Cost

  Institution

Name
Dartmouth College
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755

  Publications

Parker, Zachary M; Pasieka, Tracy Jo; Parker, George A et al. (2016) Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure. J Virol 90:10789-10799
Allegrezza, Michael J; Rutkowski, Melanie R; Stephen, Tom L et al. (2016) Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis. Cancer Res 76:6253-6265
Rosato, Pamela C; Katzenell, Sarah; Pesola, Jean M et al. (2016) Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency. Virology 497:323-327
O'Connor, Megan A; Vella, Jennifer L; Green, William R (2016) Reciprocal relationship of T regulatory cells and monocytic myeloid-derived suppressor cells in LP-BM5 murine retrovirus-induced immunodeficiency. J Gen Virol 97:509-22
Yeager, Mark P; Pioli, Patricia A; Collins, Jane et al. (2016) Glucocorticoids enhance the in vivo migratory response of human monocytes. Brain Behav Immun 54:86-94
Ball, Michael S; Shipman, Emilie P; Kim, Hyunjung et al. (2016) CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages. PLoS One 11:e0149600
Katzenell, Sarah; Leib, David A (2016) Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons. J Virol 90:4706-4719
Patankar, Yash R; Mabaera, Rodwell; Berwin, Brent (2015) Differential ASC requirements reveal a key role for neutrophils and a noncanonical IL-1? response to Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 309:L902-13
Parker, Zachary M; Murphy, Aisling A; Leib, David A (2015) Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1. J Virol 89:11080-91
Rosato, Pamela C; Leib, David A (2015) Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis. PLoS Pathog 11:e1005028

Showing the most recent 10 out of 129 publications