Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The West Virginia University (WVU) Flow Cytometry Core Facility was established in 2002 as part of the Center for Biomedical Research Excellence (COBRE) grant in Signal Transduction and Cancer. The Flow Cytometry Core Facility offers analytic flow cytometry and cell sorting to WVU and neighboring institutions, and supports COBRE investigators as well as other NIH-funded projects. In the past 3 years the facility has supported research leading to 23 peer-reviewed publications and over 20 abstracts. This application describes 1) the Facility s history, current instrumentation, and personnel, 2) the Core Facility Operational Plan, 3) the contribution of the Core Facility in fulfilling research objectives of COBRE-funded and other projects at WVU, 4) the Facility s role in current and future cancer-related projects including research projects described in the COBRE grant renewal application, and 5) a report on successful efforts at obtaining funding for a state of the art cell FACSAria cell sorter.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
2P20RR016440-06
Application #
7381271
Study Section
Special Emphasis Panel (ZRR1-RI-8 (01))
Project Start
2006-09-15
Project End
2007-06-30
Budget Start
2006-09-15
Budget End
2007-06-30
Support Year
6
Fiscal Year
2006
Total Cost
$168,104
Indirect Cost

  Institution

Name
West Virginia University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506

  Publications

Nichols, Cody E; Shepherd, Danielle L; Hathaway, Quincy A et al. (2018) Reactive oxygen species damage drives cardiac and mitochondrial dysfunction following acute nano-titanium dioxide inhalation exposure. Nanotoxicology 12:32-48
Shumar, Stephanie A; Kerr, Evan W; Geldenhuys, Werner J et al. (2018) Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform. J Biol Chem 293:4134-4148
Bedenbaugh, M N; O'Connell, R C; Lopez, J A et al. (2018) Kisspeptin, gonadotrophin-releasing hormone and oestrogen receptor ? colocalise with neuronal nitric oxide synthase neurones in prepubertal female sheep. J Neuroendocrinol 30:
Rodgers, H M; Huffman, V J; Voronina, V A et al. (2018) The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification. Mech Dev 151:18-29
Brooks, Celine; Snoberger, Aaron; Belcastro, Marycharmain et al. (2018) Archaeal Unfoldase Counteracts Protein Misfolding Retinopathy in Mice. J Neurosci 38:7248-7254
Grisez, Brian T; Ray, Justin J; Bostian, Phillip A et al. (2018) Highly metastatic K7M2 cell line: A novel murine model capable of in vivo imaging via luciferase vector transfection. J Orthop Res :
Deng, Wentao; McLaughlin, Sarah L; Klinke, David J (2017) Quantifying spontaneous metastasis in a syngeneic mouse melanoma model using real time PCR. Analyst 142:2945-2953
Alway, Stephen E; McCrory, Jean L; Kearcher, Kalen et al. (2017) Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women. J Gerontol A Biol Sci Med Sci 72:1595-1606
Alway, Stephen E; Mohamed, Junaith S; Myers, Matthew J (2017) Mitochondria Initiate and Regulate Sarcopenia. Exerc Sport Sci Rev 45:58-69
Haramizu, Satoshi; Asano, Shinichi; Butler, David C et al. (2017) Dietary resveratrol confers apoptotic resistance to oxidative stress in myoblasts. J Nutr Biochem 50:103-115

Showing the most recent 10 out of 306 publications