This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The AR INBRE's Science Research Core is comprised of services provided by three scientific research facilities. These core facilities provide investigators throughout the state with access to the instrumentation and expertise needed for three key areas of modern biotechnology. All three areas were chosen because the technical expertise and, especially, the instrumentation of each facility are not commonly available, even in an average, well-funded research laboratory. Yet, all three facilities represent areas of research at the molecular and cellular level in which rapid advances are occurring daily. With access to these technologies for specific studies and/or collection of data, researchers can pursue and extend their research projects in their own laboratories. Each Biotechnology Core facility is committed to the education and training of both INBRE faculty and students (undergraduate and graduate) in the sophisticated technologies specific to each facility. The three facilities and their goals are: Genomics: Provide expertise and equipment to allow researchers to incorporate genotypic and gene expression analyses into existing studies and to design new studies using state-of-the-art genetic tools. Proteomics: Provide expertise and equipment to enable researchers to study protein structure using state-of-the-art instrumentation. Digital Microscopy: Provide expertise and equipment to allow researchers to locate macromolecules within cells and tissues, thereby better assessing their function in normal and diseased states.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
2P20RR016460-09
Application #
8168095
Study Section
Special Emphasis Panel (ZRR1-RI-7 (01))
Project Start
2010-05-19
Project End
2011-04-30
Budget Start
2010-05-19
Budget End
2011-04-30
Support Year
9
Fiscal Year
2010
Total Cost
$290,699
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Physiology
Type
Schools of Medicine
DUNS #
122452563
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Doyle, Erin L; Fillman, Christy L; Reyna, Nathan S et al. (2018) Genome Sequences of Four Cluster P Mycobacteriophages. Genome Announc 6:
McSweeney, Jean C; Hudson, Teresa J; Prince, Latrina et al. (2018) Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas. Adv Physiol Educ 42:123-129
Wolyniak, Michael J; Reyna, Nathan S; Plymale, Ruth et al. (2018) Mass Spectrometry as a Tool to Enhance ""-omics"" Education. J Microbiol Biol Educ 19:
Musa, Aliyu; Ghoraie, Laleh Soltan; Zhang, Shu-Dong et al. (2018) A review of connectivity map and computational approaches in pharmacogenomics. Brief Bioinform 19:506-523
Caviness, Perry; Bauer, Ryan; Tanaka, Keisuke et al. (2018) Ca2+ -induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation. FEBS J 285:3254-3269
Hill, Brent J F; Dalton, Robin J; Joseph, Biny K et al. (2017) 17?-estradiol reduces Cav 1.2 channel abundance and attenuates Ca2+ -dependent contractions in coronary arteries. Pharmacol Res Perspect 5:
Allison, Devin; Delancey, Evan; Ramey, Hunter et al. (2017) Synthesis and antimicrobial studies of novel derivatives of 4-(4-formyl-3-phenyl-1H-pyrazol-1-yl)benzoic acid as potent anti-Acinetobacter baumannii agents. Bioorg Med Chem Lett 27:387-392
MacNicol, Melanie C; Cragle, Chad E; McDaniel, F Kennedy et al. (2017) Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2. Sci Rep 7:11503
Gao, Bo; Li, Guojun; Liu, Juntao et al. (2017) Identification of driver modules in pan-cancer via coordinating coverage and exclusivity. Oncotarget 8:36115-36126
Rahmatallah, Yasir; Zybailov, Boris; Emmert-Streib, Frank et al. (2017) GSAR: Bioconductor package for Gene Set analysis in R. BMC Bioinformatics 18:61

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