This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.This Bioinformatics Core will build on the progress made by the BRIN program to create and expand infrastructure and provide bioinformatics tools for network investigators. The repertoire of bioinformatics tools that were made available during BRIN will be augmented with additional licensed and open source tools. The computational infrastructure to support this range of tools will be substantially increased. In addition, the training program for this core will be greatly expanded relative to cover the new tools and infrastructure that the core will provide. As a consequence of reallocation of resources, there will be a greater degree of expert support in terms of training and mentoring made available to the network investigators. The Bioinformatics Core will also leverage other ongoing outreach activities with synergistic potential at the University of South Carolina, Medical University of South Carolina, and Clemson University funded by other agencies to maximize the effectiveness of the aggregate effort. We will also work closely with Claflin and Furman Universities in the development of their recently-funded bioinformatics programs.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016461-08
Application #
7720400
Study Section
Special Emphasis Panel (ZRR1-RI-4 (02))
Project Start
2008-05-01
Project End
2009-04-30
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
8
Fiscal Year
2008
Total Cost
$170,305
Indirect Cost
Name
University of South Carolina at Columbia
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041387846
City
Columbia
State
SC
Country
United States
Zip Code
29208
Liang, Jiaxin; Chen, Mengqian; Hughes, Daniel et al. (2018) CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases. Cancer Res 78:6594-6606
Emetu, Sophia; Troiano, Morgan; Goldmintz, Jacob et al. (2018) Metabolic Labeling and Profiling of Transfer RNAs Using Macroarrays. J Vis Exp :
Oprisan, Sorinel A; Buhusi, Mona; Buhusi, Catalin V (2018) A Population-Based Model of the Temporal Memory in the Hippocampus. Front Neurosci 12:521
Germany, Edward M; Zahayko, Nataliya; Huebsch, Mason L et al. (2018) The AAA ATPase Afg1 preserves mitochondrial fidelity and cellular health by maintaining mitochondrial matrix proteostasis. J Cell Sci 131:
Turner, J Phillip; Chastain, Shelby E; Park, Dongwon et al. (2017) Modulating amyloid-? aggregation: The effects of peptoid side chain placement and chirality. Bioorg Med Chem 25:20-26
Karousou, Evgenia; Misra, Suniti; Ghatak, Shibnath et al. (2017) Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer. Matrix Biol 59:3-22
Taylor, Nicholas G; Swenson, Samantha; Harris, Nicholas J et al. (2017) The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly. J Biol Chem 292:1815-1825
Lamba, Vandana; Sanchez, Enis; Fanning, Lauren Rose et al. (2017) Kemp Eliminase Activity of Ketosteroid Isomerase. Biochemistry 56:582-591
Krout, Danielle; Pramod, Akula Bala; Dahal, Rejwi Acharya et al. (2017) Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs. Biochem Pharmacol 142:204-215
Waddell, Grace L; Gilmer, Caroline R; Taylor, Nicholas G et al. (2017) The eukaryotic enzyme Bds1 is an alkyl but not an aryl sulfohydrolase. Biochem Biophys Res Commun 491:382-387

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