Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Electrical activity plays an important role in regulating the growth and development of the nervous system. For example, ongoing electrical activity plays an important role in the regulation of neuronal survival, axon outgrowth, neurotransmitter expression, and electrical differentiation of developing neurons. This proposal is designed to test the role of electrical activity in regulating gene expression in lumbar motoneurons. Inhibition of electrical activity will be performed by expression of the inward rectifier potassium channel Kir2.1. Changes in gene expression will be assessed using the Affymetrix GeneChip Chicken Genome Array

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
2P20RR016462-09
Application #
8168179
Study Section
Special Emphasis Panel (ZRR1-RI-7 (01))
Project Start
2010-08-01
Project End
2011-05-31
Budget Start
2010-08-01
Budget End
2011-05-31
Support Year
9
Fiscal Year
2010
Total Cost
$4,262
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Wagner, Benjamin A; Braddick, Valerie C; Batson, Christopher G et al. (2018) Effects of testosterone dose on spatial memory among castrated adult male rats. Psychoneuroendocrinology 89:120-130
Mireault, Gina C; Crockenberg, Susan C; Heilman, Keri et al. (2018) Social, cognitive, and physiological aspects of humour perception from 4 to 8 months: Two longitudinal studies. Br J Dev Psychol 36:98-109
Mireault, Gina C; Rainville, Brady S; Laughlin, Breanna (2018) Push or Carry? Pragmatic Opportunities for Language Development in Strollers vs. Backpacks. Infancy 23:616-624
Mireault, Gina C (2017) Laughing MATTERS. Sci Am Mind 28:33-37
Nock, Adam M; Wargo, Matthew J (2016) Choline Catabolism in Burkholderia thailandensis Is Regulated by Multiple Glutamine Amidotransferase 1-Containing AraC Family Transcriptional Regulators. J Bacteriol 198:2503-14
Spritzer, M D; Curtis, M G; DeLoach, J P et al. (2016) Sexual interactions with unfamiliar females reduce hippocampal neurogenesis among adult male rats. Neuroscience 318:143-56
Hinkle, Karen L; Anderson, Chad C; Forkey, Blake et al. (2016) Exposure to the lampricide 3-trifluoromethyl-4-nitrophenol results in increased expression of carbohydrate transporters in Saccharomyces cerevisiae. Environ Toxicol Chem 35:1727-32
Reddy, Vasudevi; Mireault, Gina (2015) Teasing and clowning in infancy. Curr Biol 25:R20-3
Symeonides, Menelaos; Murooka, Thomas T; Bellfy, Lauren N et al. (2015) HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts. Viruses 7:6590-603
Xie, Yi; Jin, Yu; Merenick, Bethany L et al. (2015) Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Sci Signal 8:ra44

Showing the most recent 10 out of 178 publications