This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The University of Nevada Las Vegas (UNLV) has been operating the Genomics and Imaging Core laboratories for approximately 4 years, and has recently become home to the Cytometry Core Laboratory. To streamline services and administration of these cores, they have been unified as the Central Research Services Core. This multi-user, fee-for-service facility houses state-of-the-art genomics equipment including: a Bio-Rad iCycler RT-PCR machine, an Amersham multimode imager, and glass slide and Affymetrix microarray platforms. The cytometer is a Becton Dickinson FACSCalibur, and the imaging equipment includes a Zeiss LSM-510 confocal laser scanning microscopy system. The centralized core has been funded with infrastructure awards from the NSF (EPS-0132556; $3.38M) and the NIH (2 P20 RR016464) with the goal of facilitating new lines of research and improving current research programs. Investigators studying genetic, cellular, molecular, physiological processes in biomedical and evolutionary contexts regularly use the facilities. With 21 registered users and new users being trained by the center's professional staff on a regular basis, the center is among the most heavily-utilized common-use facilities on the UNLV campus. No equivalent facilities exist within several hundred kilometers of UNLV. The core has also strengthened our training of postdoctoral, graduate and undergraduate students, improving their competitive ability and maturation as scientists. The facility director and technicians are responsible for (1) maintaining equipment in optimal working order, (2) administering user access, (3) organizing the training of new users, (4) updating hardware and software, (5) billing and accounting and (6) procurement of additional of funds to ensure that the facility continues to meet the needs of our research community. The INBRE award provides funds to support the center's director, technical staff, operating costs and service contracts for major equipment.
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