This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 1. In the 12 months that I have been here, I have finished my collaboration with a Japanese group in Nagoya, Japan on hepatitis B virus molecular therapeutics. A peer reviewed publication has resulted. 2. I have established a laboratory (which includes a DNA sequencer). Administrative paper work for a post-doctoral fellow to run the lab was initiated in July 2004 and hopefully the fellow will arrive soon. Once that individual arrives, the Alaskan native project on liver cancer will commence. The fellow may also work on other topics once this initial project is underway. 3. Other research ventures are also occuring with the Alaskan Native Tribal Health Consortium to work on Alaskan native health related issues. The current project that I am working on auto-immune hepatitis. 4. Two students that I am fostering have generated data. One student is at the public health laboratories and working on the molecular epidemiology of diphtheria species, another student is finishing his work on the levels of contaminants in foods eaten by Alaskan natives and he will be presenting a seminar on this topic at George Washington University in Washington DC in early May (next week). 5. A collaboration/mentorship is starting very shortly with a hepatitis laboratory located at the School of Medicine at the University of Washington, Seattle. 6. Two research proposals have been submitted to the NIH. They are: an RO3 grant: a clinical study to be conducted on viral hepatitis in Anchorage in the non-native population; and a R21 grant: a clinical study to be conducted on the epidemiology of heart disease in Alaskan natives. 7. A possible research collaboration with Dr. Drovetski (current faculty) and Dr. Causey (the new research provost at UAA) to work on bird influenza virus is in the earlier stages and possibly something may be eventuate.'

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016466-06
Application #
7381476
Study Section
Special Emphasis Panel (ZRR1-RI-7 (02))
Project Start
2006-05-01
Project End
2007-04-30
Budget Start
2006-05-01
Budget End
2007-04-30
Support Year
6
Fiscal Year
2006
Total Cost
$200,769
Indirect Cost
Name
University of Alaska Fairbanks
Department
Type
Organized Research Units
DUNS #
615245164
City
Fairbanks
State
AK
Country
United States
Zip Code
99775
Wilson, Robert E; Ely, Craig R; Talbot, Sandra L (2018) Flyway structure in the circumpolar greater white-fronted goose. Ecol Evol 8:8490-8507
Hueffer, Karsten; Khatri, Shailesh; Rideout, Shane et al. (2017) Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. Sci Rep 7:12818
Ely, Craig R; Wilson, Robert E; Talbot, Sandra L (2017) Genetic structure among greater white-fronted goose populations of the Pacific Flyway. Ecol Evol 7:2956-2968
Talbot, Sandra L; Sage, George K; Sonsthagen, Sarah A et al. (2017) Intraspecific evolutionary relationships among peregrine falcons in western North American high latitudes. PLoS One 12:e0188185
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Vayndorf, Elena M; Scerbak, Courtney; Hunter, Skyler et al. (2016) Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis. NPJ Aging Mech Dis 2:
Goldsmith, Elizabeth W; Renshaw, Benjamin; Clement, Christopher J et al. (2016) Population structure of two rabies hosts relative to the known distribution of rabies virus variants in Alaska. Mol Ecol 25:675-88
Leewis, Mary-Cathrine; Uhlik, Ondrej; Leigh, Mary Beth (2016) Synergistic Processing of Biphenyl and Benzoate: Carbon Flow Through the Bacterial Community in Polychlorinated-Biphenyl-Contaminated Soil. Sci Rep 6:22145

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