This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Biomedical Research Focus in 25 words or less. Wildlife Toxicology Laboratory is contaminants, health & nutrition of subsistence use & wildlife. We are not solely 'research' we are involved with diagnostics/problem solving.1. Update on science, proposals/grants, projects.Proposals/Grants:CANHR (COBRE) renewal funded ($1.2KK over 5 years for our assessment of nutrients and contaminants in salmon, reindeer, and bearded seals in Mekoryuk).IACUC protocol 06-20 Approval 06/07/2007IACUC protocol 07-09 Approval 01/16/2008IACUC protocol 07-30 Approval 06/12/2007IACUC protocol 07-37 Approval 08/14/2007IACUC protocol 07-49 Approval 12/18/2007IACUC protocol 08-02 Approval 01/17/2008NSF major proposal ($2+ million, O'Hara PI) submitted January 2007 in response to the rfp 'Ecology of Infectious Diseases' entitled 'Modeling apex predator disease agents at the arctic Alaska marine-terrestrial interface'. NOT FUNDED.NIH R01: Two major efforts underwayTwo species fish model for perchlorate submitted combining efforts of UAA (PI Von Hippel), University of Oregon and UAF to determine underlying mechanism for masculinization of stickleback fish from exposure to perchlorate. Please discuss details with Frank at UAA.Hg in Fish of Alaska: R01 in preparation under guidance of mentors Gary Myers and Dave Eaton, and EAC member Jim Berner (JB likely Co-Inv). Likely to involve direct human sampling and assessment!Non-NIH, Non-NSF (those less prestigious awards)Harbor seals: Hoonah Indian Association (USFWS funds) and National Park Service Cooperative agreement combine for about $250K: because of 75% decline in population of harbor seals in Glacier Bay (Alaska) we have been asked to assist with health, disease and contaminants assessment  pathways to humans. Ms. Darce Holcomb is the MS student on this.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016466-08
Application #
7719956
Study Section
Special Emphasis Panel (ZRR1-RI-7 (02))
Project Start
2008-05-01
Project End
2009-04-30
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
8
Fiscal Year
2008
Total Cost
$193,235
Indirect Cost
Name
University of Alaska Fairbanks
Department
Type
Organized Research Units
DUNS #
615245164
City
Fairbanks
State
AK
Country
United States
Zip Code
99775
Wilson, Robert E; Ely, Craig R; Talbot, Sandra L (2018) Flyway structure in the circumpolar greater white-fronted goose. Ecol Evol 8:8490-8507
Hueffer, Karsten; Khatri, Shailesh; Rideout, Shane et al. (2017) Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. Sci Rep 7:12818
Ely, Craig R; Wilson, Robert E; Talbot, Sandra L (2017) Genetic structure among greater white-fronted goose populations of the Pacific Flyway. Ecol Evol 7:2956-2968
Talbot, Sandra L; Sage, George K; Sonsthagen, Sarah A et al. (2017) Intraspecific evolutionary relationships among peregrine falcons in western North American high latitudes. PLoS One 12:e0188185
Leewis, Mary-Cathrine; Uhlik, Ondrej; Fraraccio, Serena et al. (2016) Differential Impacts of Willow and Mineral Fertilizer on Bacterial Communities and Biodegradation in Diesel Fuel Oil-Contaminated Soil. Front Microbiol 7:837
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Hoffman, M; Taylor, B E; Harris, M B (2016) Evolution of lung breathing from a lungless primitive vertebrate. Respir Physiol Neurobiol 224:11-6
Vayndorf, Elena M; Scerbak, Courtney; Hunter, Skyler et al. (2016) Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis. NPJ Aging Mech Dis 2:
Goldsmith, Elizabeth W; Renshaw, Benjamin; Clement, Christopher J et al. (2016) Population structure of two rabies hosts relative to the known distribution of rabies virus variants in Alaska. Mol Ecol 25:675-88
Leewis, Mary-Cathrine; Uhlik, Ondrej; Leigh, Mary Beth (2016) Synergistic Processing of Biphenyl and Benzoate: Carbon Flow Through the Bacterial Community in Polychlorinated-Biphenyl-Contaminated Soil. Sci Rep 6:22145

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