Abstract

This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The shared instrument core was designed to expand institutional research facilties by developing the infrastructure for (a) a laboratory capable of cell culture and other microbial and biochemical projects and (b) a laboratory capable of analytical and semi-preparative HPLC-MS-ELSD (high performance liquid chromatography with mass spectrometric and evaporative light scattering detectors) and other chemical research in order to support biomedical research among faculty at Hawaii Pacific University and neighboring institutions. These greatly expanded capabilites will allow additional faculty in both biology and chemistry to effectively develop preliminary research projects and respond to RFPs for extramural funding. The proposed expansion of HPU's research capability builds on significant institutional commitment and supports a proposed Junior Investigator research project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016467-08
Application #
7725233
Study Section
Special Emphasis Panel (ZRR1-RI-7 (02))
Project Start
2008-05-01
Project End
2009-04-30
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
8
Fiscal Year
2008
Total Cost
$139,088
Indirect Cost

  Institution

Name
University of Hawaii
Department
Type
Schools of Medicine
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822

  Publications

Kaholokula, Joseph Keawe'aimoku; Antonio, Mapuana C K; Ing, Claire K Townsend et al. (2017) The effects of perceived racism on psychological distress mediated by venting and disengagement coping in Native Hawaiians. BMC Psychol 5:2
Yu, Xufen; Zhang, Mingming; Annamalai, Thirunavukkarasu et al. (2017) Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors. Eur J Med Chem 125:515-527
Jarvi, Susan I; Bianchi, Kiara R; Farias, Margaret Em et al. (2016) Characterization of class II ? chain major histocompatibility complex genes in a family of Hawaiian honeycreepers: 'amakihi (Hemignathus virens). Immunogenetics 68:461-475
Sun, Zuyue; Schriewer, Jill; Tang, Mingxin et al. (2016) The TGF-? pathway mediates doxorubicin effects on cardiac endothelial cells. J Mol Cell Cardiol 90:129-38
Youn, Ui Joung; Sripisut, Tawanun; Park, Eun-Jung et al. (2015) Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum. Bioorg Med Chem Lett 25:4719-23
Miklossy, Gabriella; Youn, Ui Joung; Yue, Peibin et al. (2015) Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin ?-2 Expression, and Induce Antitumor Effects against Human Glioma. J Med Chem 58:7734-48
Panee, Jun (2015) Potential Medicinal Application and Toxicity Evaluation of Extracts from Bamboo Plants. J Med Plant Res 9:681-692
Panee, Jun; Pang, Xiaosha; Munsaka, Sody et al. (2015) Independent and co-morbid HIV infection and Meth use disorders on oxidative stress markers in the cerebrospinal fluid and depressive symptoms. J Neuroimmune Pharmacol 10:111-21
Rueli, Rachel H L H; Parubrub, Arlene C; Dewing, Andrea S T et al. (2015) Increased selenoprotein P in choroid plexus and cerebrospinal fluid in Alzheimer's disease brain. J Alzheimers Dis 44:379-83
Hamad, Mazen Lee; Engen, William; Morris, Kenneth R (2015) Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium. Pharm Dev Technol 20:314-9

Showing the most recent 10 out of 142 publications