This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Kathleen Schell Overall Rationale for Studies: Accurate blood pressure measurement is essential to appropriate healthcare. 1.The Effects of Anatomical Structures on Adult Forearm and Upper Arm Automatic, Non-invasive Blood Pressures Background & rationale: Forearm oscillometric blood pressures are sometimes used when available cuffs do not fit the upper arm or the upper arm is inaccessible. Studies have demonstrated that forearm and upper arm BPs are not interchangeable for some adults. Identification of these individuals is elusive as results have shown no correlation to clinical or demographic factors. Study questions: Are forearm and upper arm blood pressures interchangeable? What factors influence differences in forearm and upper arm blood pressures? Design: descriptive comparison study Study population: Twenty subjects between 18 and 25 years without peripheral vascular disease or coronary artery disease Outcome measures: Body mass indices; Systolic, diastolic, and mean blood pressure for forearm and upper arm; Upper arm and forearm circumferences, skinfold measurements, ultrasound measurements of vessel depth and diameter. Percent of arm subcutaneous tissue as determined Dual Energy X-ray Absortiometry. 2. A Clinical Comparison of Upper Arm and Calf Automatic Non-invasive Blood Pressures in Pediatric Intensive Care Patients Background & Rationale: Calf BPs are used in children when the upper arm is not accessible and/or when nurses do not want to disturb children while they are resting in the Pediatric Intensive Care Unit (PICU). There have been varied findings regarding the accuracy of these readings. Study Questions: Are calf and arm oscillometric BPs interchangeable in critically ill children? Design: descriptive comparison study Study Population: 300 patients between 1 and 8 years of age admitted to a pediatric ICU Outcome Measures: Calf and arm systolic, diastolic, and mean blood pressures. 3. Comparison of Forearm and Upper Arm Automatic, Non-invasive Blood Pressures in Critically Ill Adults Background & rationale: The use of forearm oscillometric blood pressures has been observed in acute health care settings, including intensive care units. Research does not consistently support this practice and studies including critically ill adults have not been conducted. Study questions: Are forearm and upper arm oscillometric blood pressures interchangeable in critically ill adults? What demographic and clinical factors influence the relationship of forearm and upper arm blood pressures? How does body position affect the relationship of forearm and upper arm blood pressures? Design: descriptive comparison study Study population: 200 English and/or Spanish speaking patients, 18 years of age or older, who are admitted to a 14-bed intensive care unit in The Chester County Hospital in West Chester, PA. Outcome measures: Forearm and upper arm oscillometric systolic, diastolic, and mean blood pressures.
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