Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Faculty Research Development Awards (FRDAs): To enhance the research base at WV-INBRE Primarily Undergraduate Institutions (PUIs), we provide funds to support biomedical research projects to be carried out at the PUIs. These grants benefit the WV-INBRE as a whole as well as the PUIs, and each focused on a biomedical research project. Project proposals could be for initiation of a new research endeavor or to continue an ongoing project. Individual investigators at each PUI could apply for a maximum of award of $50,000. Funded projects were required to involve undergraduates in the research. Continuation of funding for previously funded projects required solid evidence of research progress.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016477-11
Application #
8360179
Study Section
Special Emphasis Panel (ZRR1-RI-4 (01))
Project Start
2011-05-01
Project End
2012-04-30
Budget Start
2011-05-01
Budget End
2012-04-30
Support Year
11
Fiscal Year
2011
Total Cost
$475,705
Indirect Cost

  Institution

Name
Marshall University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
036156615
City
Huntington
State
WV
Country
United States
Zip Code
25701

  Publications

Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves attenuate chemotherapy-resistant ovarian cancer stem cell traits via targeting the Wnt/?-catenin signaling pathway and inducing G1 cell cycle arrest. Food Funct 9:525-533
Gao, Ying; Yin, Junfeng; Rankin, Gary O et al. (2018) Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells. Molecules 23:
Pan, Haibo; Li, Jin; Rankin, Gary O et al. (2018) Synergistic effect of black tea polyphenol, theaflavin-3,3'-digallate with cisplatin against cisplatin resistant human ovarian cancer cells. J Funct Foods 46:1-11
Zhang, Shichao; Xing, Malcolm M Q; Li, Bingyun (2018) Capsule Integrated Polypeptide Multilayer Films for Effective pH-Responsive Multiple Drug Co-Delivery. ACS Appl Mater Interfaces :
Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Flavonoids from Chinese bayberry leaves induced apoptosis and G1 cell cycle arrest via Erk pathway in ovarian cancer cells. Eur J Med Chem 147:218-226
Zhang, Yu; Chen, Shiguo; Wei, Chaoyang et al. (2018) Dietary Compound Proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves inhibit angiogenesis and regulate cell cycle of cisplatin-resistant ovarian cancer cells via targeting Akt pathway. J Funct Foods 40:573-581
Alway, Stephen E; McCrory, Jean L; Kearcher, Kalen et al. (2017) Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women. J Gerontol A Biol Sci Med Sci 72:1595-1606
Amos, Deborah L; Robinson, Tanner; Massie, Melissa B et al. (2017) Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model. Biochim Biophys Acta Mol Basis Dis 1863:2293-2306
Wang, Yaomin; Compton, Casey; Rankin, Gary O et al. (2017) 3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells. Int J Oncol 50:1392-1402
Alway, Stephen E; Mohamed, Junaith S; Myers, Matthew J (2017) Mitochondria Initiate and Regulate Sarcopenia. Exerc Sport Sci Rev 45:58-69

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