SD BRIN (sponsored by the University of South Dakota School of Medicine in Vermillion, (SD) is the South Dakota component of the IDeA Networks of Biomedical Research Excellence (INBRE). This application for Phase II of INBRE has evolved from lessons learned and changes made during Phase I of SD BRIN. While the two main goals for Phase II remain essentially the same as in Phase I, they have been slightly modified and clarified to more accurately reflect the directions planned by the Network for Phase II. The vision of SD BRIN is to further develop a strong collaborative Network within South Dakota to enhance basic biomedical research capabilities via an interdisciplinary approach to research in the control of cell growth with special emphasis on proteomics and genomics. Therefore, the goals of Phase II of SD BRIN are to: 1) Develop SD research capacity in the area of control of cell growth with special emphasis on proteomics and genomics by: a) enhancing research capacity and critical mass of investigators in proteomics and genomics by mentoring junior faculty members at lead research intensive institution, b) maintaining proteomics and genomics core facilities (with professional staff) which can be used by investigators throughout SD, and c) providing increased opportunities for graduate training. 2) Develop human resources for undergraduate programs and graduate programs in the biomedical sciences and bioinformatics at South Dakota institutions by: a) providing research support and mentoring for junior investigators and faculty from participating institutions, b) providing opportunities for, and understanding of, cutting-edge scientific research for students at predominantly undergraduate institutions, c) introducing undergraduates to graduate programs and future careers in biomedical sciences and bioinformatics, and d) enhancing science and research capabilities at tribal colleges to provide opportunities for further education and careers in science and research.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016479-05
Application #
7170930
Study Section
Special Emphasis Panel (ZRR1-RI-7 (01))
Project Start
2005-07-01
Project End
2006-04-30
Budget Start
2005-07-01
Budget End
2006-04-30
Support Year
5
Fiscal Year
2005
Total Cost
$43,523
Indirect Cost
Name
University of South Dakota
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
929930808
City
Vermillion
State
SD
Country
United States
Zip Code
57069
Anderson, Ruthellen H; Lensing, Cody J; Forred, Benjamin J et al. (2018) Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells. ChemMedChem 13:1695-1710
Herrera, Andrea L; Suso, Kuta; Allison, Stephanie et al. (2017) Binding host proteins to the M protein contributes to the mortality associated with influenza-Streptococcus pyogenes superinfections. Microbiology :
Rozenblat, Vanja; Ong, Deborah; Fuller-Tyszkiewicz, Matthew et al. (2017) A systematic review and secondary data analysis of the interactions between the serotonin transporter 5-HTTLPR polymorphism and environmental and psychological factors in eating disorders. J Psychiatr Res 84:62-72
Oleas, Gabriela; Callegari, Eduardo; Sepúlveda, Romina et al. (2017) Heterologous expression, purification and characterization of three novel esterases secreted by the lignocellulolytic fungus Penicillium purpurogenum when grown on sugar beet pulp. Carbohydr Res 443-444:42-48
Oleas, Gabriela; Callegari, Eduardo; Sepulveda, Romina et al. (2016) Properties of Two Novel Esterases Identified from Culture Supernatant of Penicillium purpurogenum Grown on Sugar Beet Pulp. Insights Enzym Res 1:
Zhang, Lei; Hapon, Maria B; Goyeneche, Alicia A et al. (2016) Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors. Mol Oncol 10:1099-117
Callegari, Eduardo A (2016) Shotgun Proteomics Analysis of Estrogen Effects in the Uterus Using Two-Dimensional Liquid Chromatography and Tandem Mass Spectrometry. Methods Mol Biol 1366:131-148
Herrera, Andrea L; Huber, Victor C; Chaussee, Michael S (2016) The Association between Invasive Group A Streptococcal Diseases and Viral Respiratory Tract Infections. Front Microbiol 7:342
Bonilla, José Oscar; Callegari, Eduardo Alberto; Delfini, Claudio Daniel et al. (2016) Simultaneous chromate and sulfate removal by Streptomyces sp. MC1. Changes in intracellular protein profile induced by Cr(VI). J Basic Microbiol :
Zhang, Fan; Hartnett, Sigurd; Sample, Alex et al. (2016) High fat diet induced alterations of atrial electrical activities in mice. Am J Cardiovasc Dis 6:1-9

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