The LSU-HSC leads a partnership of fourLouisiana institutions in a COBRE on neuroscience research. The ProgramDirector and established scientists are mentors to selected, highly promisingjunior faculty who propose four research projects that have been designed forthe common goal of mentoring to build new nationally competitive research.The scientific focus is on a central issue of neurobiology: to understandthe cellular and molecular basis of synaptic plasticity and neuronal survivalcritical to clarify the pathophysiology of neurological disorders such as:stroke, neural trauma and neurodegenerative diseases. This multidisciplinaryprogram involves cellular neurophysiology, molecular biology and behavioralneuroscience. To support the COBRE projects, core resources includefacilities for imaging , neurochemistry of lipid messengers and molecularneurobiology. A recruitment plan for years 2 to 5 further benefits thecollaborating institutions by actively attracting new research faculty whowill work under the guidance of established neuroscientists as mentors. Arelatively small administrative core funding is requested.
The specific aims to attain these objectives are: 1) to promote faculty development throughresearch projects; 2) to further develop a critical mass of competitiveextramurally funded investigators by the recruitment, start up, mentoring andretention of new faculty members; 3) to enhance the infrastructure criticalfor expanding neuroscience capability in Louisiana by developing three coreresearch modules at LSUHSC; 4) to provide scientific and grantsmanshipmentoring and strengthen the support network that promotes interactions; and5) to implement interim and outcome evaluations so as to keep this COBREprogram on track. This partnership rests on existing expertise and in our firmdecision to build a scientifically successful neuroscience alliance inLouisiana. The four target faculty and the four to-be-recruited faculty arethe critical building blocks to achieve these goals. The core resources arevital to the overall success of this consortium, not only in neuroscience butin all the biomedical sciences. The plans for mentoring junior faculty andthe recruitment plan will ensure a steady stream of new nationally competitiveneuroscientists in Louisiana.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016816-04
Application #
7171010
Study Section
Special Emphasis Panel (ZRR1-RI-A (01))
Project Start
2005-02-01
Project End
2006-01-31
Budget Start
2005-02-01
Budget End
2006-01-31
Support Year
4
Fiscal Year
2005
Total Cost
$108,667
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Neurology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
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