This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Administrative/Educational Core of the CBBO/SD has facilitated the research and training goals of the COBRE during this initial funding period by: (1) To schedule and organize meetings for the CBBO/SD participants; (2) To organize meetings of the Scientific Advisory Committee (SAC); (3) To provide fiscal administration and accounting; (4) To interface with institutional administration in new faculty recruitment; (5) To oversee the funding of new pilot projects; (6) To interface and provide appropriate reporting to the NIH and other regulatory agencies; (7) To sponsor and organize research career development and training opportunities; and, (8) To provide outcomes assessment of the CBBO/SD. During this year, the A/E Core has initiated a monthly seminar series in collaboration with the College of Dentistry and the regional chapter of the American Association for Dental Research. This has enabled invited speakers monthly beginning Nov. 2004. We have hired a full-time Administrative Officer to manage the COBRE grant, as well as working with investigators across the College of Dentistry to enhance grant submission and the quality of grants management. We have organized a review of both the YIP/OHP (pilot) Grants by the SAC, as well as a replacement project for Project #3 that was funded via an R01. The A/E Core is also developing a solicitation for a second round of YIP/OHP and currently hast 3 new junior faculty preparing applications for these pilot grants. The A/E Core has also developed with the junior investigators and mentors, tools for assessment of needs and expectations relative to the maturation of the investigators as academic faculty. These tools have been administered to obtain initial information from the group, so as to provide yearly monitoring of changing needs. The A/E Core has also begun work with the UK K30 award group to develop training and career development opportunities with shared resources and interacting groups of faculty and fellows, particularly as related to clinical research and faculty development.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR020145-03
Application #
7382112
Study Section
Special Emphasis Panel (ZRR1-RI-5 (02))
Project Start
2006-08-01
Project End
2007-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
3
Fiscal Year
2006
Total Cost
$178,297
Indirect Cost
Name
University of Kentucky
Department
Dentistry
Type
Schools of Dentistry
DUNS #
939017877
City
Lexington
State
KY
Country
United States
Zip Code
40506
Gonzalez, O A; Kirakodu, S; Novak, M J et al. (2018) Comparative analysis of microbial sensing molecules in mucosal tissues with aging. Immunobiology 223:279-287
Ebersole, J L; Dawson 3rd, D A; Emecen Huja, P et al. (2018) Age and Periodontal Health - Immunological View. Curr Oral Health Rep 5:229-241
Danaher, Robert J; Zhang, Liping; Donley, Connor J et al. (2018) Histone deacetylase inhibitors prevent persistent hypersensitivity in an orofacial neuropathic pain model. Mol Pain 14:1744806918796763
Ebersole, Jeffrey L; Orraca, Luis; Kensler, Terry B et al. (2018) Periodontal disease susceptible matrilines in the Cayo Santiago Macaca mulatta macaques. J Periodontal Res :
Ebersole, J L; Kirakodu, S; Novak, M J et al. (2018) Comparative analysis of expression of microbial sensing molecules in mucosal tissues with periodontal disease. Immunobiology :
Ebersole, Jeffrey L; Al-Sabbagh, Mohanad; Gonzalez, Octavio A et al. (2018) Ageing effects on humoral immune responses in chronic periodontitis. J Clin Periodontol 45:680-692
Lyons, Danielle N; Zhang, Liping; Pandya, Jignesh D et al. (2018) Combination Drug Therapy of Pioglitazone and D-cycloserine Attenuates Chronic Orofacial Neuropathic Pain and Anxiety by Improving Mitochondrial Function Following Trigeminal Nerve Injury. Clin J Pain 34:168-177
Lyons, Danielle N; Zhang, Liping; Danaher, Robert J et al. (2017) PPAR? Agonists Attenuate Trigeminal Neuropathic Pain. Clin J Pain 33:1071-1080
Nagarajan, R; Miller, C S; Dawson 3rd, D et al. (2017) Cross-talk between clinical and host-response parameters of periodontitis in smokers. J Periodontal Res 52:342-352
Ebersole, J L; Kryscio, R J; Campbell, C et al. (2017) Salivary and serum adiponectin and C-reactive protein levels in acute myocardial infarction related to body mass index and oral health. J Periodontal Res 52:419-427

Showing the most recent 10 out of 83 publications