Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Molecular and Cellular Analysis Core (Core C) is directed by Dr. Mark Jutila and provides Flow Cytometry and Confocal Microscopy support to COBRE projects and researchers from other departments on campus. Additional expertise in biotechnology is provided to researchers and students through informal and formal course work, technical assistance, and new equipment to expand and support research projects. These technologies and assistance are an integral part of most biological and molecular research programs, and therefore, are crucial to the success of the Center for Immunotherapies to Zoonotic Diseases. Indeed, the capability of sorting infectious organisms represents a strong link with the main focus of the COBRE program. Further, the Molecular and Cellular Analysis Core complements the BL-3 Level Animal Containment Core (Core D) to create a seamless and comprehensive support system to the COBRE program.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR020185-03
Application #
7382188
Study Section
Special Emphasis Panel (ZRR1-RI-5 (02))
Project Start
2006-08-01
Project End
2007-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
3
Fiscal Year
2006
Total Cost
$159,471
Indirect Cost

  Institution

Name
Montana State University - Bozeman
Department
Veterinary Sciences
Type
Schools of Earth Sciences/Natur
DUNS #
625447982
City
Bozeman
State
MT
Country
United States
Zip Code
59717

  Publications

de Jong, Nienke W M; Ramyar, Kasra X; Guerra, Fermin E et al. (2017) Immune evasion by a staphylococcal inhibitor of myeloperoxidase. Proc Natl Acad Sci U S A 114:9439-9444
Guerra, Fermin E; Borgogna, Timothy R; Patel, Delisha M et al. (2017) Epic Immune Battles of History: Neutrophils vs. Staphylococcus aureus. Front Cell Infect Microbiol 7:286
Siemsen, Dan W; Dobrinen, Erin; Han, Soo et al. (2016) Vascular Dysfunction in Pneumocystis-Associated Pulmonary Hypertension Is Related to Endothelin Response and Adrenomedullin Concentration. Am J Pathol 186:259-69
Guerra, Fermin E; Addison, Conrad B; de Jong, Nienke W M et al. (2016) Staphylococcus aureus SaeR/S-regulated factors reduce human neutrophil reactive oxygen species production. J Leukoc Biol 100:1005-1010
Hedges, Jodi F; Robison, Amanda; Kimmel, Emily et al. (2016) Type I Interferon Counters or Promotes Coxiella burnetii Replication Dependent on Tissue. Infect Immun 84:1815-1825
Zurek, Oliwia W; Pallister, Kyler B; Voyich, Jovanka M (2015) Staphylococcus aureus Inhibits Neutrophil-derived IL-8 to Promote Cell Death. J Infect Dis 212:934-8
Pallister, Kyler B; Mason, Sara; Nygaard, Tyler K et al. (2015) Bovine CCL28 Mediates Chemotaxis via CCR10 and Demonstrates Direct Antimicrobial Activity against Mastitis Causing Bacteria. PLoS One 10:e0138084
Hoyt, Teri R; Dobrinen, Erin; Kochetkova, Irina et al. (2015) B cells modulate systemic responses to Pneumocystis murina lung infection and protect on-demand hematopoiesis via T cell-independent innate mechanisms when type I interferon signaling is absent. Infect Immun 83:743-58
Prigge, Justin R; Hoyt, Teri R; Dobrinen, Erin et al. (2015) Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice. J Immunol 195:5347-57
Heinemann, Joshua; Noon, Brigit; Mohigmi, Mohammad J et al. (2014) Real-time digitization of metabolomics patterns from a living system using mass spectrometry. J Am Soc Mass Spectrom 25:1755-62

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