Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff.
Specific Aim 1 : To create a core facility that will assist all of the COBRE scientists in the design and implementation of biomechanical testing methods, including those required to evaluate articular cartilage and growth plate integrity, and overall joint function.
Specific Aim 2 : To provide the resources (i.e. space, equipment, and personnel) necessary to perform all of the biomechanical testing required by the COBRE projects.
Specific Aim 3 : To create a long-term platform to enhance the interaction between the Project PIs, the Core Directors, and external resources relating to biomechanical testing and analyses.
Specific Aim 4 : To extend the bioengineering services to the general hospital and university communities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR024484-05
Application #
8360473
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2011-08-01
Project End
2012-09-09
Budget Start
2011-08-01
Budget End
2013-07-31
Support Year
5
Fiscal Year
2011
Total Cost
$196,283
Indirect Cost

  Institution

Name
Rhode Island Hospital
Department
Type
DUNS #
075710996
City
Providence
State
RI
Country
United States
Zip Code
02903

  Publications

Gil, Joseph A; Chambers, Alison; Shah, Kalpit N et al. (2018) A Biomechanical Evaluation of a 2-Suture Anchor Repair Technique for Thumb Metacarpophalangeal Joint Ulnar Collateral Ligament Injuries. Hand (N Y) 13:581-585
Nacca, Christopher; Gil, Joseph A; Badida, Rohit et al. (2018) Critical Glenoid Bone Loss in Posterior Shoulder Instability. Am J Sports Med 46:1058-1063
Mansuripur, P Kaveh; Gil, Joseph A; Cassidy, Dale et al. (2018) Fixation Strength in Full and Limited Fixation of Osteoporotic Distal Radius Fractures. Hand (N Y) 13:461-465
Larson, K M; Zhang, L; Badger, G J et al. (2017) Early genetic restoration of lubricin expression in transgenic mice mitigates chondrocyte peroxynitrite release and caspase-3 activation. Osteoarthritis Cartilage 25:1488-1495
Gil, Joseph A; Ebert, Kerry; Blanchard, Keri et al. (2017) Efficacy of a radial-based thumb metacarpophalangeal-stabilizing orthosis for protecting the thumb metacarpophalangeal joint ulnar collateral ligament. J Hand Ther :
Chin, K E; Karamchedu, N P; Patel, T K et al. (2016) Comparison of micro-CT post-processing methods for evaluating the trabecular bone volume fraction in a rat ACL-transection model. J Biomech 49:3559-3563
Got, C; Vopat, B G; Mansuripur, P K et al. (2016) The effects of partial carpal fusions on wrist range of motion. J Hand Surg Eur Vol 41:479-83
Karamchedu, Naga Padmini; Tofte, Josef N; Waller, Kimberly A et al. (2016) Superficial zone cellularity is deficient in mice lacking lubricin: a stereoscopic analysis. Arthritis Res Ther 18:64
Li, Pengcui; Deng, Jin; Wei, Xiaochun et al. (2016) Blockade of hypoxia-induced CXCR4 with AMD3100 inhibits production of OA-associated catabolic mediators IL-1? and MMP-13. Mol Med Rep 14:1475-82
Proffen, Benedikt L; Sieker, Jakob T; Murray, Martha M et al. (2016) Extracellular matrix-blood composite injection reduces post-traumatic osteoarthritis after anterior cruciate ligament injury in the rat. J Orthop Res 34:995-1003

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