Abstract

? Clinical Core (CC) The Clinical Core is critical to the function of the Indiana Alzheimer Disease Center. Its role is to recruit, clinically characterize and longitudinally follow patients with MCI, AD, non-AD and mixed dementia and healthy controls. A major emphasis is to identify and clinically characterize patients in the presymptomatic and prodromal stages including those from familial AD and non-AD dementia kindreds. These patients will be further characterized by the Neuroimaging, Genetics, Biomarker and Bioinformatics and Neuropathology Cores. Patients from the Clinical Core will be offered as appropriate participation in ADNI, DIAN, LOAD, investigational drug trials and other local and multicenter research studies. We will continue to support NACC, NCRAD and other local, regional, national and international projects. In addition, we will collaborate with the Research Education Component and Recruitment and Education Cores to provide education and training opportunities to researchers and trainees at all levels and to educate and support affected participants, family members, and the community at large.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG010133-30
Application #
9977794
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
30
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Mustafa, Rafid; Brosch, Jared R; Rabinovici, Gil D et al. (2018) Patient and Caregiver Assessment of the Benefits From the Clinical Use of Amyloid PET Imaging. Alzheimer Dis Assoc Disord 32:35-42
Brent, Robert J (2018) Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia. Appl Econ 50:6327-6340
Kaur, Antarpreet; Edland, Steven D; Peavy, Guerry M (2018) The MoCA-Memory Index Score: An Efficient Alternative to Paragraph Recall for the Detection of Amnestic Mild Cognitive Impairment. Alzheimer Dis Assoc Disord 32:120-124
Austrom, Mary Guerriero; Boustani, Malaz; LaMantia, Michael A (2018) Ongoing Medical Management to Maximize Health and Well-being for Persons Living With Dementia. Gerontologist 58:S48-S57
Brenowitz, Willa D; Han, Fang; Kukull, Walter A et al. (2018) Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. Neurobiol Aging 62:64-71
Deming, Yuetiva; Dumitrescu, Logan; Barnes, Lisa L et al. (2018) Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol 136:857-872
Kinnunen, Kirsi M; Cash, David M; Poole, Teresa et al. (2018) Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study. Alzheimers Dement 14:43-53
Lee, Younghee; Han, Seonggyun; Kim, Dongwook et al. (2018) Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease. AMIA Jt Summits Transl Sci Proc 2017:124-131
Tometich, Danielle; Small, Brent J; Carroll, Judith E et al. (2018) Pre-treatment psychoneurological symptoms and their association with longitudinal cognitive function and quality of life in older breast cancer survivors. J Pain Symptom Manage :
Wachinger, Christian; Nho, Kwangsik; Saykin, Andrew J et al. (2018) A Longitudinal Imaging Genetics Study of Neuroanatomical Asymmetry in Alzheimer's Disease. Biol Psychiatry 84:522-530

Showing the most recent 10 out of 604 publications