- Data Management and Statistics Core (Data Core) The Data Management and Statistics Core (Data Core) for the Indiana Alzheimer Disease Center (IADC) is the central repository for data collected by all IADC cores. Data Core members provide crucial support to all research activities conducted by the multidisciplinary IADC investigator team. The Data Core maintains an integrated data management system using cutting edge technology for the daily functioning of all IADC cores and for contributing data to collaborative research initiatives. The Data Core has submitted the Uniform Data Set (UDS), neuropathology, neuroimaging and biomarker data to the National Alzheimer Coordinating Center (NACC) on a regular basis and provided data to other national collaborative studies. The Data Core provides continued statistical support to IADC investigators in Alzheimer's related research and core members also conduct independent statistical research. In this competing renewal application, the Data Core plans to continue to provide comprehensive data management functions using advanced technology for storing, accessing, reporting and sharing data collected by all cores of the IADC. The Data Core will also continue to provide statistical leadership and support to IADC and associated investigators on dementia and Alzheimer related projects. In addition, the Data Core will also provide training and mentoring in statistical methods to junior faculty, research fellows, and Ph.D. students in AD related research. The Data Core will ensure cooperation, concurrence and collaboration from the initial specification of data content to database management and data analysis, and it will enhance the IADC's capacities in the fight against AD-related dementia.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG010133-30
Application #
9977796
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
30
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Zhou, Zilu; Wang, Weixin; Wang, Li-San et al. (2018) Integrative DNA copy number detection and genotyping from sequencing and array-based platforms. Bioinformatics 34:2349-2355
Ridge, Perry G; Wadsworth, Mark E; Miller, Justin B et al. (2018) Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping. Alzheimers Dement 14:514-519
Burke, Shanna L; Hu, Tianyan; Fava, Nicole M et al. (2018) Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging :1-25
Di Fede, Giuseppe; Catania, Marcella; Maderna, Emanuela et al. (2018) Molecular subtypes of Alzheimer's disease. Sci Rep 8:3269
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169
Konar, Arpita; Kumar, Ashish; Maloney, Bryan et al. (2018) A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling. Sci Rep 8:9928
Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Burke, Shanna L; Cadet, Tamara; Maddux, Marlaina (2018) Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults. J Natl Med Assoc 110:314-325

Showing the most recent 10 out of 604 publications