SPECIFIC AIMS To enable rapid pursuit of innovative research by support of pilot projects in the Basic Biology of Aging. These awards will also be used to assist junior faculty career development and the recruitment of senior faculty not previously involved in aging research to the field of the biology of aging.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG013280-14
Application #
7651129
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
14
Fiscal Year
2008
Total Cost
$139,271
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Walters, Ryan O; Arias, Esperanza; Diaz, Antonio et al. (2018) Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Rep 25:663-676.e6
Kramer, Philip A; Duan, Jicheng; Gaffrey, Matthew J et al. (2018) Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Redox Biol 17:367-376
Kaeberlein, Matt (2018) How healthy is the healthspan concept? Geroscience 40:361-364
Crane, Matthew M; Kaeberlein, Matt (2018) The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells. Curr Opin Syst Biol 8:25-31
Beaupere, Carine; Dinatto, Leticia; Wasko, Brian M et al. (2018) Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proc Natl Acad Sci U S A 115:9586-9591
Andeen, Nicole K; Yang, Han-Yin; Dai, Dao-Fu et al. (2018) DnaJ Homolog Subfamily B Member 9 Is a Putative Autoantigen in Fibrillary GN. J Am Soc Nephrol 29:231-239
Kapahi, Pankaj; Kaeberlein, Matt; Hansen, Malene (2017) Dietary restriction and lifespan: Lessons from invertebrate models. Ageing Res Rev 39:3-14
Lee, Mitchell B; Carr, Daniel T; Kiflezghi, Michael G et al. (2017) A system to identify inhibitors of mTOR signaling using high-resolution growth analysis in Saccharomyces cerevisiae. Geroscience 39:419-428
Chen, Kenneth L; Crane, Matthew M; Kaeberlein, Matt (2017) Microfluidic technologies for yeast replicative lifespan studies. Mech Ageing Dev 161:262-269
Pino, Lindsay K; Searle, Brian C; Bollinger, James G et al. (2017) The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics. Mass Spectrom Rev :

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