Abstract

Public Health Relevance

The Research Development Core is a required component of the Nathan Shock Center. By providing support to Center faculty in the form of pilot grants, and salary/supplies to support emerging technologies in faculty research in aging, the Core acts to expand the scope of research in the basic biology of aging at UTHSCSA and to maintain the preeminence of this institution in the field of aging research. By mentoring new investigators, the Core helps to create the next generation of researchers in biological gerontology.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG013319-16
Application #
8100946
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2 (M1))
Project Start
2010-08-15
Project End
2015-06-30
Budget Start
2010-08-15
Budget End
2011-06-30
Support Year
16
Fiscal Year
2010
Total Cost
$211,197
Indirect Cost

  Institution

Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229

  Publications

Hook, Michael; Roy, Suheeta; Williams, Evan G et al. (2018) Genetic cartography of longevity in humans and mice: Current landscape and horizons. Biochim Biophys Acta Mol Basis Dis 1864:2718-2732
Van Skike, Candice E; Galvan, Veronica (2018) A Perfect sTORm: The Role of the Mammalian Target of Rapamycin (mTOR) in Cerebrovascular Dysfunction of Alzheimer's Disease: A Mini-Review. Gerontology 64:205-211
Kraig, Ellen; Linehan, Leslie A; Liang, Hanyu et al. (2018) A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects. Exp Gerontol 105:53-69
Ungvari, Zoltan; Tarantini, Stefano; Donato, Anthony J et al. (2018) Mechanisms of Vascular Aging. Circ Res 123:849-867
Weiss, Roxanne; Fernandez, Elizabeth; Liu, Yuhong et al. (2018) Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice. Aging (Albany NY) :
Qin, Kunhua; Zhang, Ning; Zhang, Zhao et al. (2018) SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice. Diabetologia 61:906-918
Salmon, Adam B; Dorigatti, Jonathan; Huber, Hillary F et al. (2018) Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. Geroscience 40:269-278
Gelfond, Jonathan; Goros, Martin; Hernandez, Brian et al. (2018) A System for an Accountable Data Analysis Process in R. R J 10:6-21
Sills, Aubrey M; Artavia, Joselyn M; DeRosa, Brian D et al. (2018) Long-term treatment with the mTOR inhibitor rapamycin has minor effect on clinical laboratory markers in middle-aged marmosets. Am J Primatol :e22927
Xu, Ming; Pirtskhalava, Tamar; Farr, Joshua N et al. (2018) Senolytics improve physical function and increase lifespan in old age. Nat Med 24:1246-1256

Showing the most recent 10 out of 231 publications