In November 2004 the Wake Forest University OAIC was awarded a competitive supplement to provide coordinating functions on behalf of the OAIC program. The supplement was renewed in September 2006, and we seek to continue and expand our functions with this renewal. On behalf of the entire OAIC program, the Coordinating Center Core (CCC) at the Wake Forest University OAIC will execute the following specific aims: 1. Provide administrative / logistical support for the OAIC program 2. Enhance the OAIC website (www.peppercenter.org) as an administrative tool for the OAIC program and develop the site to serve as an interface with the lay public, a resource for researchers in aging and related areas, and a forum for scientific exchange among OAIC investigators across sites 3. Work with NIA staff and OAIC Directors to develop and implement shared resources, and facilitate the sharing of scientific resources with other NIA/NIH center programs and with the broader scientific community 4. Provide logistical and educational support for OAIC trainees 5. Enhance the OAIC career development programs and coordinate related programs of career development sponsored by organizations committed to clinical and translational research in aging 6. Develop and pilot an OAIC Research Network to foster communications, cooperative arrangements, and collaborative projects among OAIC sites and between OAlCs and other institutional research centers, NIA- or NIH-funded research infrastructures, and other Federal or private organizations promoting geriatrics training and/or research 7. Evaluate and improve all Coordinating Center functions and activities As part of the renewal we plan to lead two major programmatic initiatives: 1) enhanced OAIC junior faculty development through: i) the coordination of the OAIC faculty development activities with other junior faculty development programs in aging, and ii) increased cross-center interactions using internet technology and a Visiting Professorship Mentoring Program;and 2) enhanced potential of the OAIC program to function as a research network through: i) the appointment of an OAIC Research Network Advisory Committee, ii) development of a web-based infrastructure for multi-institutional studies, and iii) the conduct of one or two small pilot studies to determine the feasibility and cost estimates for developing such a network.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG021332-08
Application #
8077933
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
8
Fiscal Year
2010
Total Cost
$100,595
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157
Schoell, S L; Weaver, A A; Beavers, D P et al. (2018) Development of Subject-Specific Proximal Femur Finite Element Models Of Older Adults with Obesity to Evaluate the Effects of Weight Loss on Bone Strength. J Osteoporos Phys Act 6:
Callahan, Kathryn E; Lovato, Laura; Miller, Michael E et al. (2018) Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc 66:1927-1933
Haykowsky, Mark J; Nicklas, Barbara J; Brubaker, Peter H et al. (2018) Regional Adipose Distribution and its Relationship to Exercise Intolerance in Older Obese Patients Who Have Heart Failure With Preserved Ejection Fraction. JACC Heart Fail 6:640-649
Messier, Stephen P; Resnik, Allison E; Beavers, Daniel P et al. (2018) Intentional Weight Loss in Overweight and Obese Patients With Knee Osteoarthritis: Is More Better? Arthritis Care Res (Hoboken) 70:1569-1575
Fanning, Jason; Walkup, Michael P; Ambrosius, Walter T et al. (2018) Change in health-related quality of life and social cognitive outcomes in obese, older adults in a randomized controlled weight loss trial: Does physical activity behavior matter? J Behav Med 41:299-308
Nunez Lopez, Yury O; Messi, Maria Laura; Pratley, Richard E et al. (2018) Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. Exp Gerontol 108:35-40
Liu, Zuyun; Hsu, Fang-Chi; Trombetti, Andrea et al. (2018) Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial. BMC Med 16:185
Stacey, R Brandon; Vera, Trinity; Morgan, Timothy M et al. (2018) Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals. J Cardiovasc Magn Reson 20:75
Bakhru, Rita N; Davidson, James F; Bookstaver, Rebecca E et al. (2018) Physical function impairment in survivors of critical illness in an ICU Recovery Clinic. J Crit Care 45:163-169
Custodero, C; Mankowski, R T; Lee, S A et al. (2018) Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis. Ageing Res Rev 46:42-59

Showing the most recent 10 out of 603 publications