The overall goal of the Yale Research Career Development Core (RCDC) is to identify and train a cadre of junior investigators who will be future leaders in aging research, with the skills necessary to design/conduct biological, translational, and clinical studies of multifactorial geriatric health conditions.
The specific aims are: (1) to promote the career development and acquisition of research skills of selected junior faculty through the provision of salary, infrastructure/technical, and other career development support;(2) to provide and facilitate priority access by junior faculty to the resource cores'expertise and services for the design, conduct, and analysis of studies addressing multifactorial geriatric health conditions;(3) to promote the development of skills for translational research (basic ??clinical ??basic;clinical ?>practice) that addresses our focus on multifactorial geriatric health conditions;(4) to identify and foster opportunities for interdisciplinary research;(5) to sponsor a yearly junior faculty retreat that provides intensive training and support in research career development;(6) to provide and facilitate access to educational activities in aging research locally and nationally;and (7) to enhance access to other career development resources, such as protocol development, information on funding sources, grant resource library, suitable mentors and collaborators, appropriate study populations, and geriatric instrument catalog. As reflected in these aims, there will be a greater emphasis during the next funding cycle on translational and interdisciplinary research. Dr. Thomas Gill, an NIH-funded clinical investigator with international stature for his work on functional decline and disability and with proven leadership and mentorship abilities, will lead the RCDC. For the first year, 4 candidates of outstanding promise, representing different disciplines with diverse backgrounds and interests, have been selected: Sarwat Chaudhry, MD (General Medicine), Manisha Juthani-Mehta, MD (Infectious Disease), Arthur Simen, MD, PhD (Molecular Psychiatry and Human Genetics), and Ji Li, PhD (Cardiology). Successful renewal of the Older Americans Independence Center (OAIC) will allow us to build on many of the successful procedures that we have established over the past 15 years and to continue to address the scarcity of clinical, translational and basic science investigators with optimal skills and training to rigorously study the etiology, prognosis and management of multifactorial geriatric health conditions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG021342-08
Application #
8075493
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
8
Fiscal Year
2010
Total Cost
$380,046
Indirect Cost
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Liu, Zu-Yun; Wei, Yin-Zhi; Wei, Li-Qing et al. (2018) Frailty transitions and types of death in Chinese older adults: a population-based cohort study. Clin Interv Aging 13:947-956
Monin, Joan K; Xu, Annie; Mitchell, Hannah-Rose et al. (2018) Recalling support provision decreases distress and anger in response to partner suffering. Aging Ment Health 22:587-594
Gill, Thomas M; Gahbauer, Evelyne A; Leo-Summers, Linda et al. (2018) Days Spent at Home in the Last Six Months of Life Among Community-Living Older Persons. Am J Med :
Wang, Christina; Stephens-Shields, Alisa J; DeRogatis, Leonard R et al. (2018) Validity and Clinically Meaningful Changes in the Psychosexual Daily Questionnaire and Derogatis Interview for Sexual Function Assessment: Results From the Testosterone Trials. J Sex Med 15:997-1009
Marini, Sandro; Devan, William J; Radmanesh, Farid et al. (2018) 17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage. Stroke 49:1618-1625
Buford, Thomas W; Manini, Todd M; Kairalla, John A et al. (2018) Mitochondrial DNA Sequence Variants Associated With Blood Pressure Among 2 Cohorts of Older Adults. J Am Heart Assoc 7:e010009
McCoy, Rozalina G; Herrin, Jeph; Lipska, Kasia J et al. (2018) Recurrent hospitalizations for severe hypoglycemia and hyperglycemia among U.S. adults with diabetes. J Diabetes Complications 32:693-701
Shook, Brett A; Wasko, Renee R; Rivera-Gonzalez, Guillermo C et al. (2018) Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair. Science 362:
Miller, Michael E; Magaziner, Jay; Marsh, Anthony P et al. (2018) Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations. J Am Geriatr Soc 66:954-961

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