The goal of the Research Career Development Core (RCD Core) is to recruit, train, mentor, and develop future research leaders with skills in translational research and clinical investigation directed at exploring approaches to understand and modify multiple pathways of functional decline. Previous experience with our OAlC-supported Research Development Core has taught us that we must aggressively develop and recruit promising junior faculty to enter the field of aging research. Promising scientists will be recruited to develop and/or expand their investigative skills with an emphasis on translating basic research findings into clinical studies or, taking clinical research findings and posing new basic research questions. RCD Core awardees will take courses tailored to their specific career needs, receive mentoring from senior faculty members, and receive leadership training to prepare them for key positions in geriatrics and gerontology. Our mentoring plan is designed to motivate clinical investigators to explore basic research principles and basic scientists to interface with clinical researchers. The RCD Core will ensure that its awardees take advantage of other OAIC research cores and other experienced investigators at Duke University Medical Center. RCD Core awardees will participate in OAIC seminars and conferences where interdisciplinary investigators discuss their work. In these settings, ideas for translational collaborations are raised and discussed, resulting in new projects and studies. Close collaborative links with other programs and centers at Duke University will be available to RCD Core awardees, e.g., Duke Clinical Research Institute;Health Services Research Program, VAMC;Established Population for Epidemiologic Studies of the Elderly;RAND/Hartford Interdisciplinary Geriatric Health Care Center;the Institute for Genome Sciences and Policy, and the Duke University Medical Center Mentored Clinical Research Scholar Program (MSRSP). The RCD Core will help awardees develop interdisciplinary projects and use these programs, Center and Institutes to foster translational research studies. As has occurred over the past 14 years, with previous Pepper GRTC and OAIC support, the RCD Core will produce talented, well-trained investigators to help lead the next generation of scientists in the field of aging directed at positively reorienting trajectories of functional decline in older individuals.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG028716-05
Application #
8117764
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
5
Fiscal Year
2010
Total Cost
$288,114
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Devinney, Michael J; Mathew, Joseph P; Berger, Miles (2018) Postoperative Delirium and Postoperative Cognitive Dysfunction: Two Sides of the Same Coin? Anesthesiology 129:389-391
Hall, Rasheeda K; Sloane, Richard; Pieper, Carl et al. (2018) Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease. J Am Geriatr Soc 66:532-538
Duan-Porter, Wei; Hatch, Daniel; Pendergast, Jane F et al. (2018) 12-month trajectories of depressive symptoms among nurses-Contribution of personality, job characteristics, coping, and burnout. J Affect Disord 234:67-73
Cary Jr, Michael P; Hall, Rasheeda K; Anderson, Amber L et al. (2018) Management Team Perceptions of Risks and Strategies for Preventing Falls Among Short-Stay Patients in Nursing Homes. Health Care Manag (Frederick) 37:76-85
Hall, Rasheeda K; McAdams-DeMarco, Mara A (2018) Breaking the cycle of functional decline in older dialysis patients. Semin Dial 31:462-467
Pavon, Juliessa M; Sloane, Richard J; Pieper, Carl F et al. (2018) Automated versus Manual Data Extraction of the Padua Prediction Score for Venous Thromboembolism Risk in Hospitalized Older Adults. Appl Clin Inform 9:743-751
Allen, Jason D; Vanbruggen, Mitch D; Johannsen, Neil M et al. (2018) PRIME: A Novel Low-Mass, High-Repetition Approach to Improve Function in Older Adults. Med Sci Sports Exerc 50:1005-1014
Lee, Richard H; Sloane, Richard; Pieper, Carl et al. (2018) Clinical Fractures Among Older Men With Diabetes Are Mediated by Diabetic Complications. J Clin Endocrinol Metab 103:281-287
Pastva, Amy M; Duncan, Pamela W; Reeves, Gordon R et al. (2018) Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial. Contemp Clin Trials 64:118-127
White, James P; Billin, Andrew N; Campbell, Milton E et al. (2018) The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells. Stem Cell Reports 11:425-439

Showing the most recent 10 out of 469 publications