Abstract

The Clinical Core, a fusion of the previous Patient Registry, Specimen Management, and Biostatistics Cores, will be provide a variety of services to encourage the rapid conduct of patient-based research at the NYU CFAR. The Clinical Core has the following specific purposes: To process and store biological samples from HIV-infected patients or uninfected controls; To catalog specimens stored either in the CFAR Clinical Core facilities or in the laboratories of CFAR investigators and to distribute this information in order to help CFAR investigators understand the patient- based resources available for their research; To monitor current studies so that the efficient use can be made of samples from patients of interest; To provide follow up of patients enrolled in CFAR studies; To provide epidemiological and biostatical consultation to CFAR investigators, including consultation on the use of specimens or data stored with the Clinical Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027742-07
Application #
3727214
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Type
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012

  Publications

Gornalusse, German G; Mummidi, Srinivas; Gaitan, Alvaro A et al. (2015) Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A 112:E4762-71
Miller, Elizabeth A; Gopal, Ramya; Valdes, Vanessa et al. (2015) Soluble CD40 ligand contributes to dendritic cell-mediated T-cell dysfunction in HIV-1 infection. AIDS 29:1287-96
Weiden, Michael D; Hoshino, Satomi; Levy, David N et al. (2014) Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages. PLoS One 9:e108476
Ryndak, Michelle B; Singh, Krishna K; Peng, Zhengyu et al. (2014) Transcriptional profiling of Mycobacterium tuberculosis replicating ex vivo in blood from HIV- and HIV+ subjects. PLoS One 9:e94939
Phelan, Joan A; Abrams, William R; Norman, Robert G et al. (2014) Design aspects of a case-control clinical investigation of the effect of HIV on oral and gastrointestinal soluble innate factors and microbes. PLoS One 9:e112901
Sivapalasingam, Sumathi; Mendillo, Megan; Ahmed, Aabid et al. (2014) The importance of caregivers in the outcome of pediatric HIV management, Mombasa, Kenya. AIDS Care 26:425-33
Weiser, Keren; Barton, Meredith; Gershoony, Dafna et al. (2013) HIV's Nef interacts with ?-catenin of the Wnt signaling pathway in HEK293 cells. PLoS One 8:e77865
O'Brien, Meagan; Montenont, Emilie; Hu, Liang et al. (2013) Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study. J Acquir Immune Defic Syndr 63:280-8
Rich, Josiah D; DiClemente, Ralph; Levy, Judith et al. (2013) Correctional facilities as partners in reducing HIV disparities. J Acquir Immune Defic Syndr 63 Suppl 1:S49-53
Alvarez, Yelina; Tuen, Michael; Nàdas, Arthur et al. (2012) In vitro restoration of Th17 response during HIV infection with an antiretroviral drug and Th17 differentiation cytokines. AIDS Res Hum Retroviruses 28:823-34

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