The Biometrics Core (formerly the Biostatistics Core) provides the infrastructure that facilitates an organized, synergistic, and centralized approach to statistics in AIDS research at the University of Washington and the Fred Hutchinson Cancer Research Center. In particular, the Core provides advanced statistical methods and expertise in the design, conduct and analysis of clinical research and laboratory studies to CFAR investigators. The Biometrics Core also provides a crucial link between the CFAR biomedical researchers and the large number of biostatistics and other quantitative sciences faculty at the University of Washington and the Fred Hutchinson Cancer Research Center who are developing new methods for AIDS research. The CFAR clinical, behavioral, and laboratory researchers using the Core provide datasets for analysis which motivate the development of new quantitative methods by biostatisticians, biomathematicians, engineers and computer scientists at UW and FHCRC. Hence, this link benefits CFAR investigators as well as academic quantitative science researchers. To promote and facilitate these multidisciplinary interactions the Biometrics Core 1) provides statistical and mathematical collaboration and consultation on study design, forms design, evaluation and pre-testing, data analysis, interpretation and reporting;coordinates Data Safety and Monitoring boards;provides data entry and data management services;maintains computing facilities that are available (both on site and by remote login) to any CFAR investigator;3) serves as a liaison between the Core user with advanced quantitative needs and experts from the UW Departments of Biostatistics, Statistics, Mathematics, Applied Mathematics, Engineering, and Computer Science;4) develops, adapts and/or implements new or novel statistical and mathematical methods as needed;and 5) organizes activities that promote communication among existing statisticians in HIV/AIDS research and interest from other biostatisticians that can be recruited to meet the growing demand of AIDS research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027757-25
Application #
8376313
Study Section
Special Emphasis Panel (ZAI1-EC-A)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
25
Fiscal Year
2012
Total Cost
$307,407
Indirect Cost
$81,231
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Thomson, Kerry A; Dhanireddy, Shireesha; Andrasik, Michele et al. (2018) Fertility desires and preferences for safer conception strategies among people receiving care for HIV at a publicly-funded clinic in Seattle, WA. AIDS Care 30:121-129
Lohman-Payne, Barbara; Gabriel, Benjamin; Park, Sangshin et al. (2018) HIV-exposed uninfected infants: elevated cord blood Interleukin 8 (IL-8) is significantly associated with maternal HIV infection and systemic IL-8 in a Kenyan cohort. Clin Transl Med 7:26
McGrath, Christine J; Singa, Benson; Langat, Agnes et al. (2018) Non-disclosure to male partners and incomplete PMTCT regimens associated with higher risk of mother-to-child HIV transmission: a national survey in Kenya. AIDS Care 30:765-773
Njuguna, Irene N; Wagner, Anjuli D; Omondi, Vincent O et al. (2018) Financial Incentives for Pediatric HIV Testing in Kenya. Pediatr Infect Dis J 37:1142-1144
Stone, Mars; Bainbridge, John; Sanchez, Ana M et al. (2018) Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates. J Clin Microbiol 56:
Ronen, Keshet; Unger, Jennifer A; Drake, Alison L et al. (2018) SMS messaging to improve ART adherence: perspectives of pregnant HIV-infected women in Kenya on HIV-related message content. AIDS Care 30:500-505
Duarte, Horacio A; Beck, Ingrid A; Levine, Molly et al. (2018) Implementation of a point mutation assay for HIV drug resistance testing in Kenya. AIDS 32:2301-2308
Herbeck, Joshua T; Peebles, Kathryn; Edlefsen, Paul T et al. (2018) HIV population-level adaptation can rapidly diminish the impact of a partially effective vaccine. Vaccine 36:514-520
Roberts, Sarah T; Flaherty, Brian P; Deya, Ruth et al. (2018) Patterns of Gender-Based Violence and Associations with Mental Health and HIV Risk Behavior Among Female Sex Workers in Mombasa, Kenya: A Latent Class Analysis. AIDS Behav 22:3273-3286
Bull, Marta E; Mitchell, Caroline; Soria, Jaime et al. (2018) Monotypic low-level HIV viremias during antiretroviral therapy are associated with disproportionate production of X4 virions and systemic immune activation. AIDS 32:1389-1401

Showing the most recent 10 out of 1275 publications