The mission of the Curative Therapies for HIV Scientific Working Group (SWG) is to encourage the development of a cure for HIV, by fostering new ideas and promoting new technology. During the previous funding cycle this continuing SWG was highly successful in its efforts to bring together local researchers and community members with the aim of advancing cure research. As the HIV pandemic continues to affect many millions of lives globally, there is still an urgent need for an HIV cure, so we will continue to support research into curative therapies through our SWG. The long-term objective of our SWG is to stimulate novel research, which can progress into a cure for HIV that can ultimately be transitioned into the clinic, and reduce the global burden of HIV that remains. To achieve our mission the SWG will continue to bring together UW/Fred Hutch CFAR affiliated researchers, unaffiliated external HIV researchers, and community members, through a series of scientific networking events, forums and an annual conference, each with a defined purpose. The goals of this SWG will be attained through two specific aims that are intended to: 1) Provide infrastructure that fosters the exchange of new actionable ideas, engages the community, and promotes the development of novel curative treatments for HIV, and 2) Develop new intra-/inter-CFAR projects and funding applications on curative therapies for HIV. Cooperation between researchers and community members from local, national and international settings who are invested in the common goal of HIV cure will be key to the success of our mission. We plan to leverage recent NIH investment in the Seattle-led consortium defeatHIV, one of six Martin Delaney Collaboratories focused on the cure of HIV. We will work with UW/Fred Hutch CFAR cores and external researchers to exploit expertise across many areas, in order to develop novel research questions and subsequent grant applications for the study of curative therapies for HIV. We will also work closely with local, national, and international community members to learn what an HIV cure would mean to them, and to gain new perspectives into how an HIV cure can be realized. Collaboration is essential to our mission, and by working with people of broad experience and from diverse backgrounds we hope to serve as an internationally-recognized center for the study of curative therapies for HIV.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027757-32
Application #
9693165
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2019-06-01
Budget End
2020-05-31
Support Year
32
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Boucoiran, Isabelle; Mayer, Bryan T; Krantz, Elizabeth M et al. (2018) Nonprimary Maternal Cytomegalovirus Infection After Viral Shedding in Infants. Pediatr Infect Dis J 37:627-631
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72
Fairbanks, Jade; Beima-Sofie, Kristin; Akinyi, Pamela et al. (2018) You Will Know That Despite Being HIV Positive You Are Not Alone: Qualitative Study to Inform Content of a Text Messaging Intervention to Improve Prevention of Mother-to-Child HIV Transmission. JMIR Mhealth Uhealth 6:e10671
Nevin, Paul E; Frey, Sarah; Lipira, Lauren et al. (2018) ""You are always hiding. It's the worst way to live."" Exploring Stigma in African Immigrants Living With HIV in a Large Northwest U.S. Metropolitan Area. J Assoc Nurses AIDS Care 29:417-425
Sauceda, John A; Wiebe, John S; Chan, Kiana et al. (2018) Acculturation, family cohesion, and mental health among Latinos living with HIV on the U.S.-Mexico border. Cultur Divers Ethnic Minor Psychol 24:453-458
Yanik, Elizabeth L; Hernández-Ramírez, Raúl U; Qin, Li et al. (2018) Brief Report: Cutaneous Melanoma Risk Among People With HIV in the United States and Canada. J Acquir Immune Defic Syndr 78:499-504
Kraft, John C; McConnachie, Lisa A; Koehn, Josefin et al. (2018) Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation. J Control Release 275:229-241
Suter, Megan K; Karr, Catherine J; John-Stewart, Grace C et al. (2018) Implications of Combined Exposure to Household Air Pollution and HIV on Neurocognition in Children. Int J Environ Res Public Health 15:
Jenness, Samuel M; Goodreau, Steven M; Morris, Martina (2018) EpiModel: An R Package for Mathematical Modeling of Infectious Disease over Networks. J Stat Softw 84:
Howe, Chanelle J; Dulin-Keita, Akilah; Cole, Stephen R et al. (2018) Evaluating the Population Impact on Racial/Ethnic Disparities in HIV in Adulthood of Intervening on Specific Targets: A Conceptual and Methodological Framework. Am J Epidemiol 187:316-325

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