The original UCSF Center for AIDS Research (1988-1993) supported several activities in addition to the core facilities. The most important of these was the awarding of New Investigator Award. After the initial award, we redirected Planning and Evaluation funds to support state-of- the-art Workshops and Symposia. In the final year of the grant, with the limited remaining funds, CFAR funded a small Evolving Research Opportunity proposal. Two of the activities, support for new HIV investigators and support for evolving research opportunities in HIV research, form important components of the newly restricted CFAR. In retrospect, these activities proved to be very important factors in coordinating AIDS research through the CFAR mechanism and in encouraging productive collaborations at UCSF. The current CFAR application requests funds for New Investigator Awards, Pilot Project Awards and Evolving Research Opportunities. Budgetary restrictions preclude plans for Workshops and Symposia similar to those in the original CFAR. However, we have made preliminary plans for a seminar series that would bring basic research and clinical AIDS programs together. The goal of this seminar series is to generate new ideas, foster productive interactions and encourage collaborations between basic research investigators and clinicians across the Campus community. We plan to hold the seminars four times per year in the Gladstone Institute of Virology and Immunology AIDS Research Center Conference Room. Topics currently under consideration include Therapy and Quantification of Viral Load.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI027763-06
Application #
3747011
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Martin, Jeremy W; Chen, Joseph C; Neidleman, Jason et al. (2018) Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod 99:336-348
Joglekar, Alok V; Liu, Zhe; Weber, Jeffrey K et al. (2018) T cell receptors for the HIV KK10 epitope from patients with differential immunologic control are functionally indistinguishable. Proc Natl Acad Sci U S A 115:1877-1882
Burbelo, Peter D; Price, Richard W; Hagberg, Lars et al. (2018) Anti-Human Immunodeficiency Virus Antibodies in the Cerebrospinal Fluid: Evidence of Early Treatment Impact on Central Nervous System Reservoir? J Infect Dis 217:1024-1032
Baxi, S M; Greenblatt, R M; Bacchetti, P et al. (2018) Evaluating the association of single-nucleotide polymorphisms with tenofovir exposure in a diverse prospective cohort of women living with HIV. Pharmacogenomics J 18:245-250
Adland, Emily; Hill, Matilda; Lavandier, Nora et al. (2018) Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J Virol 92:
Ferdin, Jana; Gori?ar, Katja; Dolžan, Vita et al. (2018) Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One 13:e0191613
Cohen, Stephanie E; Sachdev, Darpun; Lee, Sulggi A et al. (2018) Acquisition of tenofovir-susceptible, emtricitabine-resistant HIV despite high adherence to daily pre-exposure prophylaxis: a case report. Lancet HIV :
Altekruse, Sean F; Shiels, Meredith S; Modur, Sharada P et al. (2018) Cancer burden attributable to cigarette smoking among HIV-infected people in North America. AIDS 32:513-521
Coleman, Sharon M; Gnatienko, Natalia; Lloyd-Travaglini, Christine A et al. (2018) False-positive HIV diagnoses: lessons from Ugandan and Russian research cohorts. HIV Clin Trials 19:15-22
Faust, Tyler B; Li, Yang; Bacon, Curtis W et al. (2018) The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife 7:

Showing the most recent 10 out of 1541 publications