The primary aim of the UCSF-GIVI CFAR is to nurture and sustain innovative multidisciplinary HIV research at the intersections of the basic, clinical, behavioral and epidemiologic scientific disciplines. All decisions made within the Center are carefully measured against this research goal. The Center?s leadership reflects the scientific and geographic diversity of HIV research in San Francisco, and is committed to proactive rather than reactive management, which is greatly facilitated by regular weekly meetings and quarterly off-site strategic planning retreats. To catalyze multidisciplinary research, the Center has established seven scientific cores (Clinical, Behavioral Science and Epidemiology, Immunology, Virology, Pathology, Specimen Banking, and Pharmacology). Core Directors are charged with actively encouraging new investigators to join the multidisciplinary HIV research effort by taking advantage of the cutting-edge technologies and assays available within the core laboratories. Success of the scientific cores is measured by the quality of the multidisciplinary science they help to stimulate and by the publications and successful grants to which they contribute. Center activities are coordinated by an Administrative Core that maintains an electronic network to connect and inform all CFAR members, organizes scientific seminars and symposia, and implements financial systems that permit close monitoring of all CFAR funds, thereby ensuring that CFAR resources are used to maximum benefit. Such financial oversight has allowed the CFAR leadership, on occasion, to reallocate monies to support high priority research initiatives identified through strategic planning. The Developmental Core provides funding for pilot projects of young investigators and actively mentors them to help ensure their steady growth and development as young scientists. Developmental funds are also used to support strategic initiatives within the Center, when possible. The success of the UCSF-GIVI CFAR is evident in the scientific accomplishments of its investigators, its ability to galvanize fundamentally new science through its focus on innovative multidisciplinary HIV research, and the significant institutional support it receives from UCSF, the San Francisco Veterans Affairs Medical Center and The J. David Gladstone Institutes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
3P30AI027763-12S2
Application #
6870670
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Young, Janet M
Project Start
2002-07-15
Project End
2007-06-30
Budget Start
2004-04-01
Budget End
2004-06-30
Support Year
12
Fiscal Year
2004
Total Cost
$393,318
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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Ferdin, Jana; Gori?ar, Katja; Dolžan, Vita et al. (2018) Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One 13:e0191613
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Libby, Ashley Rg; Joy, David A; So, Po-Lin et al. (2018) Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife 7:
Haas, Andreas D; Zaniewski, Elizabeth; Anderegg, Nanina et al. (2018) Retention and mortality on antiretroviral therapy in sub-Saharan Africa: collaborative analyses of HIV treatment programmes. J Int AIDS Soc 21:
Dubé, Karine; Gianella, Sara; Concha-Garcia, Susan et al. (2018) Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics 19:83
Manuzak, Jennifer A; Gott, Toni M; Kirkwood, Jay S et al. (2018) Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals. Clin Infect Dis 66:1872-1882

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