The primary aim of the UCSF-GIVI CFAR is to nurture and sustain innovative multidisciplinary HIV research at the intersections of the basic, clinical, behavioral and epidemiologic scientific disciplines. All decisions made within the Center are carefully measured against this research goal. The Center?s leadership reflects the scientific and geographic diversity of HIV research in San Francisco, and is committed to proactive rather than reactive management, which is greatly facilitated by regular weekly meetings and quarterly off-site strategic planning retreats. To catalyze multidisciplinary research, the Center has established seven scientific cores (Clinical, Behavioral Science and Epidemiology, Immunology, Virology, Pathology, Specimen Banking, and Pharmacology). Core Directors are charged with actively encouraging new investigators to join the multidisciplinary HIV research effort by taking advantage of the cutting-edge technologies and assays available within the core laboratories. Success of the scientific cores is measured by the quality of the multidisciplinary science they help to stimulate and by the publications and successful grants to which they contribute. Center activities are coordinated by an Administrative Core that maintains an electronic network to connect and inform all CFAR members, organizes scientific seminars and symposia, and implements financial systems that permit close monitoring of all CFAR funds, thereby ensuring that CFAR resources are used to maximum benefit. Such financial oversight has allowed the CFAR leadership, on occasion, to reallocate monies to support high priority research initiatives identified through strategic planning. The Developmental Core provides funding for pilot projects of young investigators and actively mentors them to help ensure their steady growth and development as young scientists. Developmental funds are also used to support strategic initiatives within the Center, when possible. The success of the UCSF-GIVI CFAR is evident in the scientific accomplishments of its investigators, its ability to galvanize fundamentally new science through its focus on innovative multidisciplinary HIV research, and the significant institutional support it receives from UCSF, the San Francisco Veterans Affairs Medical Center and The J. David Gladstone Institutes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027763-13
Application #
6770990
Study Section
Special Emphasis Panel (ZAI1-HSD-A (J1))
Program Officer
Young, Janet M
Project Start
2002-07-15
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
13
Fiscal Year
2004
Total Cost
$2,480,262
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Tang, Weiming; Liu, Chuncheng; Cao, Bolin et al. (2018) Receiving HIV Serostatus Disclosure from Partners Before Sex: Results from an Online Survey of Chinese Men Who Have Sex with Men. AIDS Behav 22:3826-3835
Ayers, Leona W; Barbachano-Guerrero, Arturo; McAllister, Shane C et al. (2018) Mast Cell Activation and KSHV Infection in Kaposi Sarcoma. Clin Cancer Res 24:5085-5097
Tamraz, Bani; Huang, Yong; French, Audrey L et al. (2018) A Genome-Wide Association Study Identifies a Candidate Gene Associated With Atazanavir Exposure Measured in Hair. Clin Pharmacol Ther 104:949-956
Clutton, Genevieve Tyndale; Jones, R Brad (2018) Diverse Impacts of HIV Latency-Reversing Agents on CD8+ T-Cell Function: Implications for HIV Cure. Front Immunol 9:1452
Kattah, Michael G; Milush, Jeffrey M; Burt, Trevor et al. (2018) Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants. Clin Transl Gastroenterol 9:143
Jiang, Wei; Luo, Zhenwu; Martin, Lisa et al. (2018) Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy. Curr HIV Res 16:143-150
El-Sadr, Wafaa M; Goosby, Eric (2018) Building on the HIV platform: tackling the challenge of noncommunicable diseases among persons living with HIV. AIDS 32 Suppl 1:S1-S3
Lidofsky, Anna; Holmes, Jacinta A; Feeney, Eoin R et al. (2018) Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection. J Infect Dis 218:1394-1403
Dunkley, Emma; Ashaba, Scholastic; Burns, Bridget et al. (2018) ""I beg you…breastfeed the baby, things changed"": infant feeding experiences among Ugandan mothers living with HIV in the context of evolving guidelines to prevent postnatal transmission. BMC Public Health 18:188
Streubel, Gundula; Watson, Ariane; Jammula, Sri Ganesh et al. (2018) The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells. Mol Cell 70:371-379.e5

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