Abstract

The Biostatistics Core serves as the centralized resource for statistical expertise and datamanagement services to support the research programs and projects conducted by the membersof the Center for AIDS Research (CFAR).
The specific aims of the Biostatistics Core are to: (a)coordinate statistical activities in CFAR to ensure that investigators have ready access to statisticalconsultation and support; (b) provide statistical and epidemiologic expertise in study designincluding research proposal development, sample size determination and power calculation,randomization procedures, data collection form design, and plans for interim and final analyses; (c)develop and manage AIDS related research databases for CFAR investigators; and (d) providestatistical analysis for CFAR projects using contemporary statistical and computing methodologies,including more recently developed capabilities in microarray and proteomics data analyses. Thecore staff expertise in Biostatistics, data management, and epidemiology has been a vitalcomponent of the developmental activities in the CFAR, proving especially helpful for our younginvestigators. The Core is operated under the specific usage policies and priority guidelinesestablished with the advice of the Advisory Committee for the Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
3P30AI027767-20S1
Application #
7697007
Study Section
Special Emphasis Panel (ZAI1-EC-A (J1))
Project Start
2008-09-16
Project End
2009-02-28
Budget Start
2008-09-16
Budget End
2009-02-28
Support Year
20
Fiscal Year
2008
Total Cost
$72,590
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Peng, Binghao J; Carlson, Jonathan M; Liu, Michael K P et al. (2018) Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection. J Virol 92:
Shi, Bi; Geng, Jianlin; Wang, Yin-Hu et al. (2018) Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4. J Immunol 200:586-594
Moshiri, Niema; Mirarab, Siavash (2018) A Two-State Model of Tree Evolution and Its Applications to Alu Retrotransposition. Syst Biol 67:475-489
Crockett, Kaylee B; Rice, Whitney S; Turan, Bulent (2018) Associations Between Multiple Forms of Discrimination and Tobacco Use Among People Living With HIV: The Mediating Role of Avoidance Coping. J Acquir Immune Defic Syndr 78:9-15
Mai, Uyen; Mirarab, Siavash (2018) TreeShrink: fast and accurate detection of outlier long branches in collections of phylogenetic trees. BMC Genomics 19:272
Tomalka, Amanda G; Resto-Garay, Ivelisse; Campbell, Kerry S et al. (2018) In vitro Evidence That Combination Therapy With CD16-Bearing NK-92 Cells and FDA-Approved Alefacept Can Selectively Target the Latent HIV Reservoir in CD4+ CD2hi Memory T Cells. Front Immunol 9:2552
Ram, Daniel R; Manickam, Cordelia; Hueber, Brady et al. (2018) Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques. PLoS Pathog 14:e1007104
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786
Rice, Whitney S; Logie, Carmen H; Napoles, Tessa M et al. (2018) Perceptions of intersectional stigma among diverse women living with HIV in the United States. Soc Sci Med 208:9-17
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72

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