The UCLA Virology/BSL3 Tissue Culture Core Laboratory provides core virology services for basic and clinical AIDS research at UCLA and serves as a user resource for studies of HIV pathogenesis and associated immune dysfunction. The Core acts as a resource for virology and tissue culture, as a focal point for development and application of novel technologies in HIV virologic diagnostic assessment, and as a bridge between clinical and basic studies conducted by UCLA investigators. The Core also provides training for new investigators in HIV biosafety level 3 (BSL3) procedures. By making the Virology/BSL3 Tissue Core facility readily available to all investigators at UCLA who are studying any aspect of HIV infection, we have fostered interactions between investigators in several departments in the UCLA School of Medicine, as well as scientists in the UCLA Schools of Dentistry and Public Health. The Virology/BSL3 Tissue Culture Core has been used by 17 different UCLA investigators who are pursuing projects involving interactions between clinical and basic science research, as well as investigator in different basic science disciplines.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI028697-06
Application #
5205398
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Bristow, Claire C; Kojima, Noah; Lee, Sung-Jae et al. (2018) HIV and syphilis testing preferences among men who have sex with men and among transgender women in Lima, Peru. PLoS One 13:e0206204
Beymer, Matthew R; DeVost, Michelle A; Weiss, Robert E et al. (2018) Does HIV pre-exposure prophylaxis use lead to a higher incidence of sexually transmitted infections? A case-crossover study of men who have sex with men in Los Angeles, California. Sex Transm Infect 94:457-462
Tylee, Daniel S; Sun, Jiayin; Hess, Jonathan L et al. (2018) Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data. Am J Med Genet B Neuropsychiatr Genet 177:641-657
Alban, Tyler J; Alvarado, Alvaro G; Sorensen, Mia D et al. (2018) Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis. JCI Insight 3:
Degtyar, Aleksandra; George, Paul E; Mallma, Patricia et al. (2018) Sexual Risk, Behavior, and HIV Testing and Status among Male and Transgender Women Sex Workers and their Clients in Lima, Peru. Int J Sex Health 30:81-91
Dovel, Kathryn; Shaba, Frackson; Nyirenda, Mike et al. (2018) Evaluating the integration of HIV self-testing into low-resource health systems: study protocol for a cluster-randomized control trial from EQUIP Innovations. Trials 19:498
DeVost, Michelle A; Beymer, Matthew R; Weiss, Robert E et al. (2018) App-Based Sexual Partner Seeking and Sexually Transmitted Infection Outcomes: A Cross-Sectional Study of HIV-Negative Men Who Have Sex With Men Attending a Sexually Transmitted Infection Clinic in Los Angeles, California. Sex Transm Dis 45:394-399
Balamurugan, Arumugam; Ng, Hwee L; Yang, Otto O (2018) Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones. J Virol 92:
Seang, Sophie; Kelesidis, Theodoros; Huynh, Diana et al. (2018) Low Levels of Endothelial Progenitor Cells and Their Association with Systemic Inflammation and Monocyte Activation in Older HIV-Infected Men. AIDS Res Hum Retroviruses 34:39-45
Kojima, Noah; Klausner, Jeffrey D (2018) Fight Fire With Fire: Innovations to Address Syphilis Among Men Who Have Sex With Men. Sex Transm Dis 45:e85-e86

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