Specific Aims 1. To facilitate the implementation of patient oriented HIV/AIDS related research at UCLA 2. To assist investigators with the regulatory aspects of biomedical and behavioral patient-oriented research 3. To establish and maintain a clinical database that will interface with the CFAR/CNICS program. The primary responsibility of the Clinical Research Facilitation Core is to facilitate the process of IRB submissions for faculty, fellows, new researchers and translational researchers who do not have a great deal of experience with human subjects research. While funding to facilities and equipment are crucial to the conduct of research, regulatory delays in the conduct of research are often overlooked. This core in itself is innovative as it provides investigators with resources not previously available to reduce delays. By its very nature, this core will support new initiatives. It will encourage research among new faculty, young faculty and fellows. The core is fully linked into the CFAR seed grant process and allows recipients to become productive in their research far earlier than if they did not have the Core to assist them. The Core has created both a website and a blog to share the resources learned while submitting applications. Additionally, the Core provides seminars to investigators and staff to increase knowledge of regulatory pitfalls and procedures. In reducing regulatory delays in. the conduct of patient-oriented research, this Core helps to maintain UCLA investigators on the cutting edge of research in HIV. PERFORMANCE SITE(S) (organization, city, state) University of California, Los Angeles Center for Clinical AIDS Research and Education 9911 W. Pico Blvd. Suite 980 Los Angeles, CA 90035 PHS 398 (Rev. 04/06) 614

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI028697-20
Application #
7795176
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2009-03-01
Budget End
2010-02-28
Support Year
20
Fiscal Year
2009
Total Cost
$90,515
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Fulcher, Jennifer A; Shoptaw, Steven; Makgoeng, Solomon B et al. (2018) Brief Report: Recent Methamphetamine Use Is Associated With Increased Rectal Mucosal Inflammatory Cytokines, Regardless of HIV-1 Serostatus. J Acquir Immune Defic Syndr 78:119-123
Walser, Tonya C; Jing, Zhe; Tran, Linh M et al. (2018) Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Res 78:1986-1999
Kojima, Noah; Klausner, Jeffrey D (2018) Improving management of sexually transmitted infections in those who use pre-exposure prophylaxis for human immunodeficiency virus infection. AIDS 32:272-275
Chua, Bernadette Anne; Ngo, Jamie Ann; Situ, Kathy et al. (2018) Protein S and Gas6 induce efferocytosis of HIV-1-infected cells. Virology 515:176-190
Allyn, P R; O'Malley, S M; Ferguson, J et al. (2018) Attitudes and potential barriers towards hepatitis C treatment in patients with and without HIV coinfection. Int J STD AIDS 29:334-340
Khamaikawin, Wannisa; Shimizu, Saki; Kamata, Masakazu et al. (2018) Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. Mol Ther Methods Clin Dev 9:23-32
Foo, Suan-Sin; Chen, Weiqiang; Chan, Yen et al. (2018) Biomarkers and immunoprofiles associated with fetal abnormalities of ZIKV-positive pregnancies. JCI Insight 3:
Gorbach, Pamina M; Javanbakht, Marjan; Bolan, Robert K (2018) Behavior change following HIV diagnosis: findings from a Cohort of Los Angeles MSM. AIDS Care 30:300-304
Rotheram-Borus, Mary Jane; Davis, Emily; Rezai, Roxana (2018) Stopping the rise of HIV among adolescents globally. Curr Opin Pediatr 30:131-136
Allan-Blitz, Lao-Tzu; Sakona, Ashyln; Wallace, William D et al. (2018) Coxiella burnetii Endocarditis and Meningitis, California, USA, 2017. Emerg Infect Dis 24:

Showing the most recent 10 out of 942 publications