Core N - The mission of the San Diego Center for AIDS Research (SD CFAR) Biostatistics and Modeling (BAM) Core is to provide quantitative expertise, collaboration, and training in the areas of biostatistics and infectious disease modeling related to HIV research. In accordance with NIH OAR priorities and our CFAR?s focus, we prioritize research in optimizing HIV care, alleviating HIV health disparities, and advancing discovery in HIV cure and vaccines. The BAM Core?s services are critical to our CFAR, as other quantitative shared resources across our institutions are generally not tailored to HIV research or focused on supporting emerging HIV investigators. Following a strategic planning process in 2016, the BAM Core was established in June 2016 as part of a restructuring of the Clinical Investigation (CI) Core and closure of the Bioinformatics and Information Technology (BIT) Core. Since its inception in June 2016, the BAM Core has provided support to 47 users (64% emerging), and 18 NIH-supported grants and supplements from 6 NIH institutes. In this short time, the BAM Core has been cited by 28 publications. The BAM Core is composed of two inter-connected units. The Biostatistics Unit handles statistical requests including pre-award statistical support and post-award collaboration. The Modeling Unit supports research involving HIV epidemic and pathogenesis modeling and health economic evaluation including pre-award support and post-award collaboration. Additionally, both units incorporate a particular focus on methodological innovation and training/mentoring in quantitative methods. The BAM Core aims are: (1) To support clinical investigation and translational HIV research by providing rigorous quantitative biostatistics support and services (Biostatistics Unit). (2) To enhance the impact of CFAR research by providing project guidance and high-level expertise on HIV infectious disease and economic modeling (Modeling Unit). (3) To encourage, mentor, and train the next generation of HIV investigators in biostatistics and modeling methodologies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI036214-26
Application #
9906068
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
26
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Jenks, Jeffrey D; Reed, Sharon L; Seidel, Danila et al. (2018) Rare mould infections caused by Mucorales, Lomentospora prolificans and Fusarium, in San Diego, CA: the role of antifungal combination therapy. Int J Antimicrob Agents 52:706-712
Drumright, Lydia N; Weir, Sharon S; Frost, Simon D W (2018) The role of venues in structuring HIV, sexually transmitted infections, and risk networks among men who have sex with men. BMC Public Health 18:225
Giamouridis, Dimosthenis; Gao, Mei Hua; Lai, N Chin et al. (2018) Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal. JACC Basic Transl Sci 3:249-264
Lin, Timothy C; Gianella, Sara; Tenenbaum, Tara et al. (2018) A Simple Symptom Score for Acute Human Immunodeficiency Virus Infection in a San Diego Community-Based Screening Program. Clin Infect Dis 67:105-111
Saag, Michael S; Günthard, Huldrych F; Smith, Davey M (2018) Baseline Genotype Testing to Assess Drug Resistance Before Beginning HIV Treatment-Reply. JAMA 320:2154
Francesconi, Walter; Berton, Fulvia; Marcondes, Maria Cecilia G (2018) HIV-1 Tat alters neuronal intrinsic excitability. BMC Res Notes 11:275
Arredondo, J; Gaines, T; Manian, S et al. (2018) The law on the streets: Evaluating the impact of Mexico's drug decriminalization reform on drug possession arrests in Tijuana, Mexico. Int J Drug Policy 54:1-8
Hoenigl, Martin; Orasch, Thomas; Faserl, Klaus et al. (2018) Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis. J Infect :
Howe, Chanelle J; Dulin-Keita, Akilah; Cole, Stephen R et al. (2018) Evaluating the Population Impact on Racial/Ethnic Disparities in HIV in Adulthood of Intervening on Specific Targets: A Conceptual and Methodological Framework. Am J Epidemiol 187:316-325
Bortell, Nikki; Basova, Liana; Najera, Julia A et al. (2018) Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. J Neuroimmune Pharmacol 13:163-178

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