Under the direction of Drs Jeffrey Lennox and Mark Mulligan, the primary goal of the Core D - ClinicalResearch Core (CRC) is to facilitate the design and implementation of clinical research studies that improveknowledge about, prevention of and treatment for, HIV infection in humans.Clinical and translational research encompasses studies involving human volunteers, clinical data, and/orhuman specimens. Core D serves Emory's NIH-funded HIV/AIDS researchers-and facilitates the entry of.new and/or junior researchers into the field. Clinical research studies may enroll HIV-infected or HIVuninfectedvolunteers in protocols focused on prevention or treatment of HIV infection. Translationalresearch bridges basic science and clinical research, often providing the earliest insights into the humansignificance of preclinical laboratory and/or animal findings. The approach taken in Core D is that humansare the 'ultimate model'. Hypotheses pertaining to studies or interventions designed to benefit mankindmust be tested in rigorous scientific fashion. Core D activities will be supported through a mixture of CFARsupport, Emory University support, charge-backs to Core D users when appropriate, and other leveragedsupport. Core D enhances the clinical and translational research activities of Emory CFAR investigatorsthrough the following Specific Aims:
Specific Aim 1. To encourage and enhance clinical and translational research studies conducted by EmoryCFAR investigators.
Specific Aim 2. To provide clinical data and human specimens to Emory CFAR clinical and translationalresearchers.
Specific Aim 3. To support the mentoring and training of new, international, and minority faculty investigatorsand research staff in the field of HIV/AIDS clinical and translational research.
Specific Aim 4. To coordinate a program of communications to Emory CFAR investigators, as well asAtlanta area communities and community investigators, about the clinical and translational researchopportunities available through Core D.
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