Under the direction of Drs Jeffrey Lennox and Mark Mulligan, the primary goal of the Core D - Clinical Research Core (CRC) is to facilitate the design and implementation of clinical research studies that improve knowledge about, prevention of and treatment for, HIV infection in humans. Clinical and translational research encompasses studies involving human volunteers, clinical data, and/or human specimens. Core D serves Emory's NIH-funded HIV/AIDS researchers-and facilitates the entry of. new and/or junior researchers into the field. Clinical research studies may enroll HIV-infected or HIVuninfected volunteers in protocols focused on prevention or treatment of HIV infection. Translational research bridges basic science and clinical research, often providing the earliest insights into the human significance of preclinical laboratory and/or animal findings. The approach taken in Core D is that humans are the """"""""ultimate model"""""""". Hypotheses pertaining to studies or interventions designed to benefit mankind must be tested in rigorous scientific fashion. Core D activities will be supported through a mixture of CFAR support, Emory University support, charge-backs to Core D users when appropriate, and other leveraged support. Core D enhances the clinical and translational research activities of Emory CFAR investigators through the following Specific Aims:
Specific Aim 1. To encourage and enhance clinical and translational research studies conducted by Emory CFAR investigators.
Specific Aim 2. To provide clinical data and human specimens to Emory CFAR clinical and translational researchers.
Specific Aim 3. To support the mentoring and training of new, international, and minority faculty investigators and research staff in the field of HIV/AIDS clinical and translational research.
Specific Aim 4. To coordinate a program of communications to Emory CFAR investigators, as well as Atlanta area communities and community investigators, about the clinical and translational research opportunities available through Core D.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050409-11
Application #
7922704
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2009-08-01
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$337,341
Indirect Cost
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Martin, Maureen P; Naranbhai, Vivek; Shea, Patrick R et al. (2018) Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest 128:1903-1912
Mustanski, Brian; Parsons, Jeffrey T; Sullivan, Patrick S et al. (2018) Biomedical and Behavioral Outcomes of Keep It Up!: An eHealth HIV Prevention Program RCT. Am J Prev Med 55:151-158
Jenness, Samuel M; Goodreau, Steven M; Morris, Martina (2018) EpiModel: An R Package for Mathematical Modeling of Infectious Disease over Networks. J Stat Softw 84:
Sam, Soya S; Caliendo, Angela M; Ingersoll, Jessica et al. (2018) Evaluation of Performance Characteristics of Panther Fusion Assays for Detection of Respiratory Viruses from Nasopharyngeal and Lower Respiratory Tract Specimens. J Clin Microbiol 56:
Eckard, Allison Ross; Raggi, Paolo; O'Riordan, Mary Ann et al. (2018) Effects of vitamin D supplementation on carotid intima-media thickness in HIV-infected youth. Virulence 9:294-305
Singleton, Robyn; Winskell, Kate; McLeod, Haley et al. (2018) Young Africans' social representations of sexual abuse of power in their HIV-related creative narratives, 2005-2014: cultural scripts and applied possibilities. Cult Health Sex :1-16
Hussen, Sophia A; Easley, Kirk A; Smith, Justin C et al. (2018) Social Capital, Depressive Symptoms, and HIV Viral Suppression Among Young Black, Gay, Bisexual and Other Men Who Have Sex with Men Living with HIV. AIDS Behav 22:3024-3032
Lahiri, Cecile D; Brown, Nakita L; Ryan, Kevin J et al. (2018) HIV RNA persists in rectal tissue despite rapid plasma virologic suppression with dolutegravir-based therapy. AIDS 32:2151-2159
Halpin, Sean N; Carruth, Edwin Clayton; Rai, Ramona P et al. (2018) Complementary and Alternative Medicine Among Persons living with HIV in the Era of Combined Antiretroviral Treatment. AIDS Behav 22:848-852
Holloway, Ian W; Bednarczyk, Robert; Fenimore, Vincent L et al. (2018) Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California. Int J Environ Res Public Health 15:

Showing the most recent 10 out of 1005 publications