Under the direction of Drs Jeffrey Lennox and Mark Mulligan, the primary goal of the Core D - Clinical Research Core (CRC) is to facilitate the design and implementation of clinical research studies that improve knowledge about, prevention of and treatment for, HIV infection in humans. Clinical and translational research encompasses studies involving human volunteers, clinical data, and/or human specimens. Core D serves Emory's NIH-funded HIV/AIDS researchers-and facilitates the entry of. new and/or junior researchers into the field. Clinical research studies may enroll HIV-infected or HIVuninfected volunteers in protocols focused on prevention or treatment of HIV infection. Translational research bridges basic science and clinical research, often providing the earliest insights into the human significance of preclinical laboratory and/or animal findings. The approach taken in Core D is that humans are the """"""""ultimate model"""""""". Hypotheses pertaining to studies or interventions designed to benefit mankind must be tested in rigorous scientific fashion. Core D activities will be supported through a mixture of CFAR support, Emory University support, charge-backs to Core D users when appropriate, and other leveraged support. Core D enhances the clinical and translational research activities of Emory CFAR investigators through the following Specific Aims:
Specific Aim 1. To encourage and enhance clinical and translational research studies conducted by Emory CFAR investigators.
Specific Aim 2. To provide clinical data and human specimens to Emory CFAR clinical and translational researchers.
Specific Aim 3. To support the mentoring and training of new, international, and minority faculty investigators and research staff in the field of HIV/AIDS clinical and translational research.
Specific Aim 4. To coordinate a program of communications to Emory CFAR investigators, as well as Atlanta area communities and community investigators, about the clinical and translational research opportunities available through Core D.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050409-13
Application #
8308423
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
13
Fiscal Year
2011
Total Cost
$295,578
Indirect Cost
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
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Haas, David W; Bradford, Yuki; Verma, Anurag et al. (2018) Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events. Pharmacogenet Genomics 28:179-187
Ke, Zunlong; Dillard, Rebecca S; Chirkova, Tatiana et al. (2018) The Morphology and Assembly of Respiratory Syncytial Virus Revealed by Cryo-Electron Tomography. Viruses 10:
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Serota, David P; Rosenberg, Eli S; Lockard, Annie M et al. (2018) Beyond the Biomedical: Preexposure Prophylaxis Failures in a Cohort of Young Black Men Who Have Sex With Men in Atlanta, Georgia. Clin Infect Dis 67:965-970
Hightow-Weidman, Lisa B; Muessig, Kathryn; Rosenberg, Eli et al. (2018) University of North Carolina/Emory Center for Innovative Technology (iTech) for Addressing the HIV Epidemic Among Adolescents and Young Adults in the United States: Protocol and Rationale for Center Development. JMIR Res Protoc 7:e10365
Reyes-Robles, Tamara; Dillard, Rebecca S; Cairns, Lynne S et al. (2018) Vibrio cholerae outer membrane vesicles inhibit bacteriophage infection. J Bacteriol :

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