The Molecular Virology Core is an essential component of the DUMC CFAR as a resource link between clinical and basic research. This core is comprised of a BSL-3 Virology Facility, a DNA Sequence Analysis Facility and a Molecular Construct Facility to serve the growing needs of Duke investigators involved in basic and clinical translational research on HIV and associated opportunistic Infections. The overall aims of the Molecular Virology Core are: 1. To facilitate the implementation and validation of molecular virology assays, DNA sequencing, and virologic assays in CFAR laboratories through shared resources in a cost efficient manner. 2. To provide state-of-the-art support for RNA interference analysis of the role of specific human genes in the replication and pathogenesis of HIV-1 or opportunistic infections. 3. To stimulate interdisciplinary collaborations within academia and industry to further improve the technology offered by the Core and to provide a solid resource on which collaborations can be fostered. 4. To provide education and training opportunities to CFAR scientists in existing and newly developed virologic methodologies. In order to achieve these aims, the Molecular Virology Core is committed to A.) maintaining a high quality of reagents and data through multiple QA/QC procedures and B.) establishing a virologic resource that is based on current and future scientific needs of CFAR investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI064518-05
Application #
7918171
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
5
Fiscal Year
2009
Total Cost
$247,599
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
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Kelly, Matthew S; Surette, Michael G; Smieja, Marek et al. (2018) Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana. Pediatr Infect Dis J 37:1176-1183
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