Abstract

; The Clinical and Translational Sciences Core (CTSC;Core C) will provide key services to UR investigators to promote collaborative clinical and translational HIV/AIDS research. The objective of the Core is to efficiently provide UR HIV/AIDS investigators direct access to human subjects research, a discipline that can be dauntingly complex and time-consuming for new investigators (including early-stage investigators, investigators new to HIV/AIDS, and basic science HIV/AIDS investigators wishing to conduct translational research). It will do so by leveraging existing infrastructure, resources and expertise, at modest incremental cost, to create broad synergies that can make a major impact on clinical and translational studies. Our experience as a D-CFAR has shown that providing that access to services alone is not necessarily sufficient to encourage new investigators to undertake translational HIV/AIDS projects. This has led us to develop a highly proactive, user-oriented, innovative approach, that includes consultation, advice and even identification and recruitment of study subjects (

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI078498-06
Application #
8520713
Study Section
Special Emphasis Panel (ZAI1-UKS-A (J1))
Project Start
2008-05-01
Project End
2018-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
6
Fiscal Year
2013
Total Cost
$240,162
Indirect Cost
$99,679

  Institution

Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

McMillan, JoEllyn; Szlachetka, Adam; Zhou, Tian et al. (2018) Pharmacokinetic testing of a first generation cabotegravir prodrug in rhesus macaques. AIDS :
Hammond, Jennetta W; Qiu, Wen Q; Marker, Daniel F et al. (2018) HIV Tat causes synapse loss in a mouse model of HIV-associated neurocognitive disorder that is independent of the classical complement cascade component C1q. Glia 66:2563-2574
Dompreh, Albert; Tang, Xiaoli; Zhou, Jianlin et al. (2018) Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis. Antimicrob Agents Chemother 62:
Leblanc, Natalie M; Mitchell, Jason (2018) Providers' Perceptions of Couples' HIV Testing and Counseling (CHTC): Perspectives From a U.S. HIV Epicenter. Couple Family Psychol 7:22-33
Rice, John D; Johnson, Brent A; Strawderman, Robert L (2018) Modeling the rate of HIV testing from repeated binary data amidst potential never-testers. Biostatistics :
Nunn, Amy; Parker, Sharon; McCoy, Katryna et al. (2018) African American Clergy Perspectives About the HIV Care Continuum: Results From a Qualitative Study in Jackson, Mississippi. Ethn Dis 28:85-92
Sillman, Brady; Bade, Aditya N; Dash, Prasanta K et al. (2018) Creation of a long-acting nanoformulated dolutegravir. Nat Commun 9:443
Ogunbajo, Adedotun; Kershaw, Trace; Kushwaha, Sameer et al. (2018) Barriers, Motivators, and Facilitators to Engagement in HIV Care Among HIV-Infected Ghanaian Men Who have Sex with Men (MSM). AIDS Behav 22:829-839
Piekna-Przybylska, Dorota; Maggirwar, Sanjay B (2018) CD4+ memory T cells infected with latent HIV-1 are susceptible to drugs targeting telomeres. Cell Cycle 17:2187-2203
Ocque, Andrew J; Hagler, Colleen E; Morse, Gene D et al. (2018) Development and validation of an LC-MS/MS assay for tenofovir and tenofovir alafenamide in human plasma and cerebrospinal fluid. J Pharm Biomed Anal 156:163-169

Showing the most recent 10 out of 192 publications