(Taken from the application): The Clinical Integration Core is a new core within the Emory Skin Disease Research Center (ESDRC) established to conduct and enhance cutaneous clinical investigation. We have three specific aims for the core.
Aim #1 : To provide infrastructure and support for investigator-initiated clinical research.
Aim #2 : To generate and maintain a patient information database centered on specific skin diseases.
Aim #3 : To facilitate the collection of cutaneous specimens for the Tissue Culture and Repository (Core B). To achieve these goals we will utilize and expand existing programs while developing new services. The Clinical Pharmacology Unit within the Department of Dermatology is currently conducting clinical trials for industry. The staff is expert in preparing and processing human investigation protocols, recruiting patients, conducting clinical research, data collection, and record keeping. This expertise will be extended to interested investigators in the academic community. Our Director and Co-Director will remain knowledgeable of ongoing clinical trials, basic science research, and clinical activities within the University. They will facilitate the exchange of information among relevant investigators. As part of our current clinical research, we collect skin disease-related information which will be valuable to those conducting basic science research. This information, along with related information collected in our various clinics, will be incorporated into a central database available to researchers in the ESDRC. Additionally, our Research Coordinator will function as a liaison between clinicians, basic scientist, and the director of the Tissue Culture and Repository (Core B) to facilitate the efficient collection of needed cutaneous specimens.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
5P30AR042687-09
Application #
6645888
Study Section
Special Emphasis Panel (ZAR1)
Project Start
2002-05-01
Project End
2003-04-30
Budget Start
Budget End
Support Year
9
Fiscal Year
2002
Total Cost
$61,783
Indirect Cost
Name
Emory University
Department
Type
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Arbiser, Jack L; Bonner, Michael Y; Gilbert, Linda C (2017) Targeting the duality of cancer. NPJ Precis Oncol 1:
Pleniceanu, Oren; Shukrun, Racheli; Omer, Dorit et al. (2017) Peroxisome proliferator-activated receptor gamma (PPAR?) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target EMBO Mol Med 9:508-530
Díaz, Begoña; Ostapoff, Katherine T; Toombs, Jason E et al. (2016) Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model. Oncotarget 7:51569-51580
Laidlaw, Kamilla M E; Berhan, Samuel; Liu, Suhu et al. (2016) Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia. Oncotarget 7:51651-51664
Bhandarkar, Sulochana S; Lanka, Padmavathy; Lanka, Lakshmana Rao et al. (2016) Tuberculosis verrucosa cutis lesions exhibit a greater microvessel count than lupus vulgaris lesions. Exp Dermatol 25:479-80
Costa, Adilson; Bonner, Michael Yi; Arbiser, Jack L (2016) Use of Polyphenolic Compounds in Dermatologic Oncology. Am J Clin Dermatol 17:369-85
Bonner, Michael Y; Karlsson, Isabella; Rodolfo, Monica et al. (2016) Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo. Oncotarget 7:12857-68
Arbiser, Jack L; Bonner, Michael Y (2016) Seborrheic Keratoses: The Rodney Dangerfield of Skin lesions, and Why They Should Get Our Respect. J Invest Dermatol 136:564-566
Arbiser, Jack L (2014) PHIPing out: a genetic basis for tumor ulceration. J Invest Dermatol 134:600-602
Spence-Shishido, Allyson; Carr, Christopher; Bonner, Michael Y et al. (2013) In vivo Gram staining of tinea versicolor. JAMA Dermatol 149:991-2

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