The goals of the Sample Procurement and Management Core (SPMC) are to optimize,promote and facilitate the research undertaken by the Center Investigators, as well as toenhance the interdisciplinary research capabilities between various Center laboratories and toexpedite human subjects research in a meaningful way. The SPMC will provide support toCenter Investigators and other users in terms of providing previously collected, de-identified,appropriately consented DMA and serum to projects, expanding DMA from existing resources orisolating additional DMA as needed from EBV-transformed cells lines, testing quality and quantityof outside and newly generated DMA and serum samples as needed, recruiting and enrollingfresh samples for project use, measuring autoantibodies in appropriate samples and managingsamples and data for the success of the Oklahoma Rheumatic Disease Research Cores Center(ORDRCC). As potential collaborators for all Core research projects, the SPMC will be anintegral part of the research team in the execution of research studies, as well as providingongoing sample and data management throughout the life of each individual project.The specific goals of the SPMC include:1. Facilitate access to human samples for research purposes. This goal includesserving as a central resource for Cores Center investigators to obtain appropriatelycollected DMA, serum, cells, clinical and de-identified clinical data.2. Facilitate human subject consent, recruitment and compliance. This goal includesconsenting, recruiting and obtaining samples from confirmation rheumatic diseasepatients for Core investigator projects, as well as assist with regulatory reporting.3. Facilitate the compilation and appropriate access to de-identified patientdemographic and clinical data from existing resources and management ofresearch data for Center Investigators. Consent, recruit and/or obtain samples fromconfirmatory lupus subsets or from patients with other systemic autoimmune rheumaticdiseases for feasibility and other projects for key Core investigators.4. Perform autoantibody testing for appropriate rheumatic disease patient sera.
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