The Administrative Core represents the executive, training, coordinating and oversight component of the Brigham and Women?s Hospital (BWH) Core Centers for Clinical Research (CCCR). The BWH CCCR, VERITY (Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics), taps into the resources of the BWH and Harvard Medical School (HMS) affiliated hospitals to offer services to the community of clinical investigators defined by the NIAMS mission, locally and nationally. The services provided by the Methods and Bioinformatics Resource Cores respond to needs we have identified for better access to a complete array of trial and bioinformatics methods organized in a streamlined and readily accessible format. The Administrative Core contains an innovative Enrichment Program to train and mentor pediatric and adult rheumatic and musculoskeletal (MSK) clinical researchers, both locally and nationally. The Enrichment Program builds on preliminary national survey data of pediatric and adult training program directors characterizing the need for clinical research training and ongoing research mentoring. The overall purpose of the VERITY Administrative Core is to develop an effective community of junior and senior investigators working toward the common goal of improving treatment and outcomes of inflammatory rheumatic and MSK disease. In addition, the Administrative Core provides scientific oversight of all aspects of the Methodology and Bioinformatics Resource Cores. These objectives are accomplished through the following Specific Aims:
Aim 1. To facilitate and supervise the scientific and administrative work of the Methodology and Bioinformatics Resource Cores, so that the needs of the Research Community are met in an efficient and responsible manner.
Aim 2. To train and mentor the next generation of clinical researchers in rheumatology. In sum, the VERITY Administrative Core will provide effective scientific and administrative oversight to ensure optimal use of the Methodology and Bioinformatics Resource Core services. Moreover, the Enrichment Program will attract, educate, and mentor the next generation of clinical researchers to enhance pediatric and adult rheumatic and MSK disease research in the US.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Center Core Grants (P30)
Project #
1P30AR072577-01
Application #
9413619
Study Section
Special Emphasis Panel (ZAR1)
Project Start
Project End
Budget Start
2017-09-01
Budget End
2018-08-31
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Cai, Tianrun; Lin, Tzu-Chieh; Bond, Allison et al. (2018) The Association Between Arthralgia and Vedolizumab Using Natural Language Processing. Inflamm Bowel Dis 24:2242-2246
Tedeschi, Sara K; Solomon, Daniel H; Liao, Katherine P (2018) Pseudogout among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease. Rheumatol Int 38:1083-1088
Luc-Harkey, Brittney A; Safran-Norton, Clare E; Mandl, Lisa A et al. (2018) Associations among knee muscle strength, structural damage, and pain and mobility in individuals with osteoarthritis and symptomatic meniscal tear. BMC Musculoskelet Disord 19:258
Alves, Kristin; Godwin, Christine L; Chen, Angela et al. (2018) Gluteal fibrosis, post-injection paralysis, and related injection practices in Uganda: a qualitative analysis. BMC Health Serv Res 18:892
Sparks, Jeffrey A; Barbhaiya, Medha; Tedeschi, Sara K et al. (2018) Inflammatory dietary pattern and risk of developing rheumatoid arthritis in women. Clin Rheumatol :
Yu, Zhi; Yang, Nicole; Everett, Brendan M et al. (2018) Impact of Changes in Inflammation on Estimated Ten-Year Cardiovascular Risk in Rheumatoid Arthritis. Arthritis Rheumatol 70:1392-1398
Hresko, Andrew; Lin, Tzu-Chieh; Solomon, Daniel H (2018) Medical Care Costs Associated With Rheumatoid Arthritis in the US: A Systematic Literature Review and Meta-Analysis. Arthritis Care Res (Hoboken) 70:1431-1438
Kreps, David J; Halperin, Florencia; Desai, Sonali P et al. (2018) Association of weight loss with improved disease activity in patients with rheumatoid arthritis: A retrospective analysis using electronic medical record data. Int J Clin Rheumtol 13:1-10
Lin, Tzu-Chieh; Yoshida, Kazuki; Tedeschi, Sara K et al. (2018) Risk of Hepatitis B Virus Reactivation in Patients With Inflammatory Arthritis Receiving Disease-Modifying Antirheumatic Drugs: A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken) 70:724-731
Yu, Zhi; Lu, Bing; Agosti, Jenifer et al. (2018) Implementation of Treat-to-Target for Rheumatoid Arthritis in the US: Analysis of Baseline Data From a Randomized Controlled Trial. Arthritis Care Res (Hoboken) 70:801-806

Showing the most recent 10 out of 17 publications