Abstract

This application is for renewal of the core grant which has provided essential support for the research program of the Sloan-Kettering Institute for Cancer Research. This is a program of cancer research, many aspects of which are closely linked with the treatment activities of our sister organization, Memorial Hospital. The core grant has provided partial support of salaries of approximately 11% of the professional staff including most of the Institute's scientific leadership, and has underwritten supporting resources such as animal maintenance services, biostatistical management, instrumentation, and other centralized activities required by a large productive scientific organization. An important provision has been the financial support necessary to develop new programs. The core support has been crucial in helping to assure stability and give a degree of flexibility not available to the Institute from University or State funds.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA008748-23
Application #
3101244
Study Section
(SRC)
Project Start
1977-01-01
Project End
1992-12-31
Budget Start
1988-01-01
Budget End
1988-12-31
Support Year
23
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Schlappe, Brooke A; Weaver, Amy L; Ducie, Jennifer A et al. (2018) Multicenter study comparing oncologic outcomes between two nodal assessment methods in patients with deeply invasive endometrioid endometrial carcinoma: A sentinel lymph node algorithm versus a comprehensive pelvic and paraaortic lymphadenectomy. Gynecol Oncol 151:235-242
Pareja, Fresia; Da Cruz Paula, Arnaud; Murray, Melissa P et al. (2018) Recurrent MED12 exon 2 mutations in benign breast fibroepithelial lesions in adolescents and young adults. J Clin Pathol :
Yao, Zhan; Gao, Yijun; Su, Wenjing et al. (2018) RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling. Nat Med :
Dumane, Vishruta A; Saksornchai, Kitwadee; Zhou, Ying et al. (2018) Reduction in low-dose to normal tissue with the addition of deep inspiration breath hold (DIBH) to volumetric modulated arc therapy (VMAT) in breast cancer patients with implant reconstruction receiving regional nodal irradiation. Radiat Oncol 13:187
Turashvili, Gulisa; Fix, Daniel J; Soslow, Robert A et al. (2018) Wilms Tumor of the Ovary: Review of the Literature and Report of 2 Cases. Int J Gynecol Pathol :
Krantz, Benjamin A; O'Reilly, Eileen M (2018) Biomarker-Based Therapy in Pancreatic Ductal Adenocarcinoma: An Emerging Reality? Clin Cancer Res 24:2241-2250
Chowell, Diego; Morris, Luc G T; Grigg, Claud M et al. (2018) Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. Science 359:582-587
Morgani, Sophie M; Metzger, Jakob J; Nichols, Jennifer et al. (2018) Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife 7:
Senders, Max L; Que, Xuchu; Cho, Young Seok et al. (2018) PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis. J Am Coll Cardiol 71:321-335
Fang, Jing; Muto, Tomoya; Kleppe, Maria et al. (2018) TRAF6 Mediates Basal Activation of NF-?B Necessary for Hematopoietic Stem Cell Homeostasis. Cell Rep 22:1250-1262

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