The Glassware Core and its 24 staff members employ over 100 pieces of equipment, throughout the Rockefeller, Schwartz and Zuckerman Research Centers, to deliver more than 5,000 pieces of cleaned and sterilized labware to more than 110 investigators and their staff. Daily routines include decontamination and collection of soiled labware;hand-scrubbing and visual inspection of each piece before further processing in commercial glasswashers;sorting, wrapping, and/or plugging followed by processing in high-temperature ovens and steam autoclaves before return to the laboratories. Specialized procedures also provide for acidwashing and RNase-free preparations. All processing follows standardized operating procedures specially adapted to meet the needs of each user, and is ascertained to meet the minimum standard of """"""""visually clean"""""""" or less than 4 ug/ml of debris, following the criteria for acceptance of LeBlanc and the FDA on the validation of cleaning processes. Over 90% of all work is restocked in each laboratory within an 8-hour time frame, providing cost and space savings to the laboratories. This core also provides dry ice stores throughout the research environment, assists with the monitoring of disposal of biohazardous waste and broken glass from laboratories, as well as provides for the decontamination of radioactive and other forms of biohazardous waste. To minimize costs to the laboratories, only """"""""hands-on"""""""" time is charged for all services. Changes are anticipated in operating procedures to allow increased standardization in washing with the use of acid and alkaline detergents in the glasswashing machines, further reducing the """"""""hands-on"""""""" time charged to users. When demand dictates, services will be expanded to include standardized cleaning of specialized laboratory equipment, such as cell and tissue incubators or freezers.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-46
Application #
8243707
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2011-01-01
Budget End
2011-12-31
Support Year
46
Fiscal Year
2011
Total Cost
$1,041,624
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Shoag, Jonathan; Liu, Deli; Blattner, Mirjam et al. (2018) SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG. J Clin Invest 128:381-386
Assel, Melissa J; Gerdtsson, Axel; Thorek, Daniel L J et al. (2018) Long-term prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age: data from the malmö preventive project. Oncotarget 9:5778-5785
Katsoulakis, Evangelia; Leeman, Jonathan E; Lok, Benjamin H et al. (2018) Long-term outcomes in oral cavity squamous cell carcinoma with adjuvant and salvage radiotherapy after surgery. Laryngoscope 128:2539-2545
Breitbart, William (2018) In Memoriam: Jimmie C. Holland, MD, 1928-2017. Palliat Support Care 16:124-126
Hoseini, Sayed Shahabuddin; Guo, Hongfen; Wu, Zhihao et al. (2018) A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia. Blood Adv 2:1250-1258
Grkovski, Milan; Fanchon, Louise; Pillarsetty, Naga Vara Kishore et al. (2018) 18F-fluoromisonidazole predicts evofosfamide uptake in pancreatic tumor model. EJNMMI Res 8:53
Tollinche, Luis; Tan, KaySee; Han, Austin et al. (2018) Analyzing Volatile Anesthetic Consumption by Auditing Fresh Gas Flow: An Observational Study at an Academic Hospital. Int J Anesth Anesth 5:
Lin, Ching-Jung; Hu, Fuqu; Dubruille, Raphaelle et al. (2018) The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline. Dev Cell 46:316-326.e5
Tadros, Audree B; Wen, Hannah Y; Morrow, Monica (2018) Breast Cancers of Special Histologic Subtypes Are Biologically Diverse. Ann Surg Oncol 25:3158-3164
Chan, Chang S; Laddha, Saurabh V; Lewis, Peter W et al. (2018) ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup. Nat Commun 9:4158

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