The Cancer Center of the Wake Forest University (CCWFU) is a multidisciplinary, interdepartmental cancer research facility. Research is organized into three divisions: 1. Division of Basic Sciences, 2. Division of Clinical Research, 3. Division of Cancer Control. Each is further subdivided into programs. The Division of Basic Sciences is composed of programs of research in Immunology and Molecular Genetics, Pharmacology, Cell Biology and Inflammation, Thrombosis and Experimental Radiation Oncology. The Division of Clinical Research has a major emphasis on technology transfer with introduction of new ideas from laboratory research to be applied in the diagnosis and treatment of cancer. These new leads stem from basic research conducted at the CCWFU, as well as at other cancer centers. Areas of special interest at the CCWFU include research in leukemia and other hematologic malignancies, breast, lung and colon cancer. In addition to clinical research conducted at the Center, a major clinical program is focused on the diffusion and application of new information into community practice through an organization known as the Piedmont Oncology Association (POA). The POA is a consortium of university and community oncologists throughout the 5-state regions of the Piedmont - North and South Carolina, Southern Virginia, Eastern Tennessee, and parts of Georgia. This Cancer Center-sponsored outreach program focuses on collaborative clinical trials and continuing education programs. In addition, the CCWFU brings protocols of a high priority fostered by the NCI and multi- university, national cooperative groups into the community. This approach offers community physicians and their patients the latest in cancer care. The Division of Cancer Control focuses on public education that will increase an awareness of cancer and will offer preventive measures and interventions for early detection. The Epidemiology Program will provide surveillance of cancer incidence in the region served by the Cancer Center in order to alert the faculty to the needs in education, prevention, and early detection. The CCWFU supports high technology core laboratories which facilitate cancer research. These include Tissue Culture, Electron Microscopy, Flow Cytometry, GC/MS, Pharmacology, NMR, Hybridoma, Oligonucleotide Synthesis Laboratory, Membrane Lipid Laboratory, and Protein Sequencing. Education in cancer is offered as a formal oncology curriculum to medical students, cancer research training for basic scientists at both the pre- and postdoctoral level and continuing education for physicians and nurses. The CCWFU has established a Cancer Patient Support Program which offers psychological supportive care to patients and their families and conducts research as to how this care might be optimized. Areas of future growth will include Molecular Genetics, Pharmacology, Immunology, Cell Biology and marrow transplantation.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA012197-21S1
Application #
2086035
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1976-03-01
Project End
1995-03-31
Budget Start
1993-02-01
Budget End
1995-03-31
Support Year
21
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Farris, Michael; McTyre, Emory R; Okoukoni, Catherine et al. (2018) Cortical Thinning and Structural Bone Changes in Non-Human Primates after Single-Fraction Whole-Chest Irradiation. Radiat Res 190:63-71
Bolduc, Jesalyn A; Nelson, Kimberly J; Haynes, Alexina C et al. (2018) Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. J Biol Chem 293:11901-11912
Garland, Mary; Addis, Dylan; Russell, Greg et al. (2018) The Effect of Regional Anesthesia on Oncologic Outcomes after Resection of Colorectal Hepatic Metastases. Am Surg 84:e29-32
Petty, W Jeffrey; Urbanic, James J; Ahmed, Tamjeed et al. (2018) Long-Term Outcomes of a Phase 2 Trial of Chemotherapy With Consolidative Radiation Therapy for Oligometastatic Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 102:527-535
Paek, M-S; Nightingale, C L; Tooze, J A et al. (2018) Contextual and stress process factors associated with head and neck cancer caregivers' physical and psychological well-being. Eur J Cancer Care (Engl) 27:e12833
Dutta, Samrat; Rivetti, Claudio; Gassman, Natalie R et al. (2018) Analysis of single, cisplatin-induced DNA bends by atomic force microscopy and simulations. J Mol Recognit 31:e2731
Pardee, Timothy S; Anderson, Rebecca G; Pladna, Kristin M et al. (2018) A Phase I Study of CPI-613 in Combination with High-Dose Cytarabine and Mitoxantrone for Relapsed or Refractory Acute Myeloid Leukemia. Clin Cancer Res 24:2060-2073
Atkins, Hannah M; Appt, Susan E; Taylor, Robert N et al. (2018) Systemic Iron Deficiency in a Nonhuman Primate Model of Endometriosis. Comp Med 68:298-307
Godwin, Ryan C; Gmeiner, William H; Salsbury Jr, Freddie R (2018) All-atom molecular dynamics comparison of disease-associated zinc fingers. J Biomol Struct Dyn 36:2581-2594
Yang, M; Forbes, M E; Bitting, R L et al. (2018) Incorporating blood-based liquid biopsy information into cancer staging: time for a TNMB system? Ann Oncol 29:311-323

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