- COMMUNITY OUTREACH AND ENGAGEMENT The Albert Einstein Cancer Center's (AECC) catchment area is the Bronx NY. The Bronx population of 1.46 million includes 10% non-Hispanic White, 30% non-Hispanic Black, and 55% Hispanic/Latino of any race, with 35% of all residents foreign born. The Bronx is one of the poorest urban counties in the US, with 28% of families living in poverty. This catchment area aligns with AECC's clinical presence and public health programming. AECC is affiliated with the Montefiore Health System, the Bronx' major clinical and public health facility. Annually, Montefiore serves ~500,000 (36%) Bronx residents. About 87% of Montefiore hospital discharges live in the Bronx. Key partners for community outreach and engagement within the Health System include: a care management organization of 3,400+ providers caring for more than 225,000 members; a practice-based primary care research network hosting 600,000 visits/year; a system-wide health education and community outreach program; and the largest and most comprehensive school health network in the US. Montefiore treated over 20,000 patients with cancer over the past 5 years, >65% ethnic and racial minorities. Montefiore cancer care provides psycho-oncology, educational, wellness, peer support and navigation programs tailored to Bronx survivors and families. There is an established AECC community council to advise patient support and outreach programs. To set priorities for COE, AECC worked with an expanded Bronx Community Cancer Advisory Board and health system partners to review AECC research along with surveillance data. The highest incidence malignancies in the Bronx are prostate, breast, colorectal and lung cancers. Cancers associated with obesity and with endemic HIV, HCV and HPV infections are of particular concern, as are stomach cancer and multiple myeloma. Smoking rates are high among people living with HIV, substance users, and others affected by social determinants of health. Low rates of screening are related to disconnection from the health system, financial insecurity, medical mistrust and negative attitudes about screening and treatment. Cancer patients experience high levels of pain, symptoms and psychological distress, as well difficulty with treatment adherence. Many survivors deal with multiple chronic conditions and require assistance managing behavioral, psychosocial and economic impact of cancer. Based on this analysis, AECC's COE will focus on Community Access and Adherence to Cancer Prevention and Screening and Cancer Care Coordination and Supportive Care.
Specific aims are: to drive local cancer prevention and control by conducting and disseminating surveillance; to enable clinical, public health and community partners to implement and evaluate annual evidence-based demonstration projects; to bring AECC investigators together with COE partners to foster novel collaborations; and to sustain and disseminate successful strategies in the catchment area and beyond. To accomplish these aims, a COE Team will work with local partners, guided by an executive-level COE Coordinating Committee with input from the Bronx Community Cancer Advisory Board.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA013330-47
Application #
9792761
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
47
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
081266487
City
Bronx
State
NY
Country
United States
Zip Code
10461
Agalliu, Ilir; Chen, Zigui; Wang, Tao et al. (2018) Oral Alpha, Beta, and Gamma HPV Types and Risk of Incident Esophageal Cancer. Cancer Epidemiol Biomarkers Prev 27:1168-1175
Bhargava, Ragini; Sandhu, Manbir; Muk, Sanychen et al. (2018) C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun 9:2484
Collu, Giovanna M; Jenny, Andreas; Gaengel, Konstantin et al. (2018) Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment. PLoS Genet 14:e1007391
Doyle, Christopher R; Moon, Jee-Young; Daily, Johanna P et al. (2018) A Capsular Polysaccharide-Specific Antibody Alters Streptococcus pneumoniae Gene Expression during Nasopharyngeal Colonization of Mice. Infect Immun 86:
Anayannis, Nicole V; Schlecht, Nicolas F; Ben-Dayan, Miriam et al. (2018) Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma. PLoS One 13:e0191581
Stepankova, Martina; Bartonkova, Iveta; Jiskrova, Eva et al. (2018) Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor. Mol Pharmacol 93:631-644
Maggi, Elaine C; Gravina, Silvia; Cheng, Haiying et al. (2018) Development of a Method to Implement Whole-Genome Bisulfite Sequencing of cfDNA from Cancer Patients and a Mouse Tumor Model. Front Genet 9:6
Ingram, Jessica R; Blomberg, Olga S; Rashidian, Mohammad et al. (2018) Anti-CTLA-4 therapy requires an Fc domain for efficacy. Proc Natl Acad Sci U S A 115:3912-3917
Dulyaninova, Natalya G; Ruiz, Penelope D; Gamble, Matthew J et al. (2018) S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms. Mol Biol Cell 29:632-642
Chen, Zigui; Schiffman, Mark; Herrero, Rolando et al. (2018) Classification and evolution of human papillomavirus genome variants: Alpha-5 (HPV26, 51, 69, 82), Alpha-6 (HPV30, 53, 56, 66), Alpha-11 (HPV34, 73), Alpha-13 (HPV54) and Alpha-3 (HPV61). Virology 516:86-101

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