The mission of the Herbert Irving Comprehensive Cancer Center is to provide the organizational infrastructure and the resources to promote interdisciplinary laboratory, clinical and population based cancer research and to facilitate the application of the research to cancer prevention, diagnosis and treatment, especially for patients in the tri- state region (Norther New Jersey, South Eastern New York and Southwestern Connecticut) served by the Cancer Center. Furthermore the Cancer Center provides education and training in cancer research for scientists, clinical investigators and health professionals at all levels as well as for patients and the lay community. These objectives are facilitated by an organizational structure that has 4 major divisions: 1) Laboratory Research; 2) Clinical Research; 3) Cancer Causation, Prevention, and Control and 4) Core Facilities. Essential support is provided by the Office of Administration and a Visiting Scientific Advisory Committee. Fields of research are organized into a total of 11 Programs that facilitate research within a given discipline and foster interdisciplinary collaboration. A major function of this grant is to support a series of 14 shared core facilities that provide state-of- the-art expertise, technology and resources with considerable efficiency and cost savings. A specific emphasis of this Cancer Center, and a unifying theme that joins together this interdisciplinary research approach, is the use of concepts and methods in cellular and molecular biology to enhance our understanding of the etiology and pathophysiology of human cancer, and to develop more effective strategies for cancer prevention, diagnosis and treatment.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA013696-30
Application #
6512514
Study Section
Subcommittee G - Education (NCI)
Program Officer
Marino, Michael A
Project Start
1976-09-01
Project End
2003-06-30
Budget Start
2002-07-23
Budget End
2003-06-30
Support Year
30
Fiscal Year
2002
Total Cost
$3,703,055
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Tzoneva, Gannie; Dieck, Chelsea L; Oshima, Koichi et al. (2018) Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia. Nature 553:511-514
Sitko, Austen A; Kuwajima, Takaaki; Mason, Carol A (2018) Eye-specific segregation and differential fasciculation of developing retinal ganglion cell axons in the mouse visual pathway. J Comp Neurol 526:1077-1096
Chen, Yen-Hua; Kratchmarov, Radomir; Lin, Wen-Hsuan W et al. (2018) Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway. Cell Rep 22:860-868
Wang, Gang; Biswas, Anup K; Ma, Wanchao et al. (2018) Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle. Nat Med 24:770-781
Cho, Galaxy Y; Schaefer, Kellie A; Bassuk, Alexander G et al. (2018) CRISPR GENOME SURGERY IN THE RETINA IN LIGHT OF OFF-TARGETING. Retina 38:1443-1455
Zyablitskaya, Mariya; Munteanu, E Laura; Nagasaki, Takayuki et al. (2018) Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking (TXL) for Myopia. J Vis Exp :
Arnes, Luis; Liu, Zhaoqi; Wang, Jiguang et al. (2018) Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma. Gut :
Petersen-Jones, Simon M; Occelli, Laurence M; Winkler, Paige A et al. (2018) Patients and animal models of CNG?1-deficient retinitis pigmentosa support gene augmentation approach. J Clin Invest 128:190-206
Sones, Jennifer L; Merriam, Audrey A; Seffens, Angelina et al. (2018) Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia. FASEB J 32:2574-2586
Park, Karen Sophia; Xu, Christine L; Cui, Xuan et al. (2018) Reprogramming the metabolome rescues retinal degeneration. Cell Mol Life Sci 75:1559-1566

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