The Computer and Informatics Resource Center (CIRC) serves the computational needs of Cancer Center researchers. Today, data for clinical and basic science studies are collected, managed and analyzed electronically. Results are then reported using a variety of software tools; the final publication is often available on-line. This information infrastructure is vital to the success of cancer research. To support this infrastructure, the CIRC staff provides expertise in both computer system and informatics. They maintain operating systems, application software, and Internet connectivity, develop and manage databases and Web services, and provide reference materials and education to end users. The emphasis of the CIRC has dramatically shifted during the last funding period from a computation-driven facility to an Internet-based informatics center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA013696-30
Application #
6616879
Study Section
Project Start
2002-07-23
Project End
2003-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
30
Fiscal Year
2002
Total Cost
$296,752
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Hernandez, Celine; Huebener, Peter; Pradere, Jean-Philippe et al. (2018) HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest 128:2436-2451
Proto, Jonathan D; Doran, Amanda C; Gusarova, Galina et al. (2018) Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity 49:666-677.e6
Kraakman, Michael J; Liu, Qiongming; Postigo-Fernandez, Jorge et al. (2018) PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest 128:2600-2612
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Dieck, Chelsea L; Tzoneva, Gannie; Forouhar, Farhad et al. (2018) Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell 34:136-147.e6
Sengillo, Jesse D; Lee, Winston; Bakhoum, Mathieu F et al. (2018) CHOROIDEREMIA ASSOCIATED WITH A NOVEL SYNONYMOUS MUTATION IN GENE ENCODING REP-1. Retin Cases Brief Rep 12 Suppl 1:S67-S71
Kratchmarov, Radomir; Viragova, Sara; Kim, Min Jung et al. (2018) Metabolic control of cell fate bifurcations in a hematopoietic progenitor population. Immunol Cell Biol 96:863-871

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